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Mulberry Compound May Modulate Blood Sugar

Posted Oct 07 2013 10:07pm

A staple remedy of folk medicine, mulberry leaf extract is found to contain the compound 1-deoxynojirimycin (DNJ) – found to inhibit the activity of the enzyme involved in carbohydrate digestion.  Hye In Chung, from Ewha Womans University (South Korea), and colleagues  enrolled 50 healthy men and women, each of whom was randomly assigned to one of five groups: four groups received a maltose powder drink containing 0, 1.25, 2.5, or 5 grams of mulberry leaf extract; the fifth group drank a beverage with 5 grams of the extract 30 minutes before consuming the maltose solution.  The team observed that  both the 2.5 and 5 gram mulberry doses lowered glucose levels. .No difference between pre- and simultaneous ingestion of mulberry extract and maltose was detected.  The study authors submit that: “The ingestion of [mulberry leaf extract] resulted in improved postprandial glycemic control in healthy subjects.”

Hye In Chung, Joohee Kim, Ji Yeon Kim, Oran Kwon.  “Acute intake of mulberry leaf aqueous extract affects postprandial glucose response after maltose loading: Randomized double-blind placebo-controlled pilot study.”  Journal of Functional Foods, Volume 5, Issue 3, July 2013, Pages 1502-1506.

  
Daily consumption of a mulberry leaf extract may lower post-meal blood sugar spikes.
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Anti-Aging Forum MLDP Join A4M
Tip #192 - Stay Connected
Researchers from the University of Chicago (Illinois, USA) report that social isolation may be detrimental to both mental and physical health. The team analyzed data from the National Social Life, Health, and Aging Project, a nationwide US study involving 3,000 men and women, ages 57 to 85 years. They arrived at three key findings regarding the relationships between health and different types of isolation:

• The researchers found that the most socially connected older adults are three times as likely to report very good or excellent health compared to those who are least connected, regardless of whether they feel isolated.

• The team found that older adults who feel least isolated are five times as likely to report very good or excellent health as those who feel most isolated, regardless of their actual level of social connectedness.

• They determined that social disconnectedness is not related to mental health unless it brings feelings of loneliness and isolation.

Separately, Rush University Medical Center (Illinois, USA) researchers studied 906 older men and women, testing their motor functions (including grip, pinch strength, balance, and walking) and surveying their social activity, for a period of 5 years. Those study participants with less social activity were found to have a more rapid rate of motor function decline. Specifically, the team found that every one-point decrease in social activity corresponded to an increase in functional aging of 5 years, translating to a 40% higher risk of death and 65% higher risk of disability.

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