Monomeric Naphthylisoquinoline Alkaloids And Synthesis Methods Thereof
Posted Feb 27 2011 7:00pm
Description of Invention: Monomeric naphthylisoquinoline alkaloids and their derivatives are medically useful for the treatment of parasitic infections including malaria. However, these particular alkaloids have been available in a limited supply since many of them could only be obtained from scarce plants which have a limited geographic distribution. This invention embodies methods for the preparation of monomeric naphthylisoquinoline alkaloids, including the antiparasitic korupensamines and related compounds, as well as non-korupensamines. Diverse new, medically useful, naphthylisoquinoline compounds and derivatives are also provided.
For Licensing Information Please Contact: Admin. Licensing Spec-InfectDis NIH Office of Technology Transfer 6011 Executive Blvd. Suite 325, Rockville, MD 20852 United States Email: anos@mail.nih.gov Phone: 301-496-7057 Fax: 301-402-0220
Description of Invention:
Monomeric naphthylisoquinoline alkaloids and their derivatives are medically useful for the treatment of parasitic infections including malaria. However, these particular alkaloids have been available in a limited supply since many of them could only be obtained from scarce plants which have a limited geographic distribution. This invention embodies methods for the preparation of monomeric naphthylisoquinoline alkaloids, including the antiparasitic korupensamines and related compounds, as well as non-korupensamines. Diverse new, medically useful, naphthylisoquinoline compounds and derivatives are also provided.
Inventors:
Michael R Boyd (NCI)
Patent Status:
HHS, Reference No. E-200-1994/0
Portfolios:
Infectious Diseases
Infectious Diseases - Therapeutics
For Licensing Information Please Contact:
Admin. Licensing Spec-InfectDis
NIH Office of Technology Transfer
6011 Executive Blvd. Suite 325,
Rockville, MD 20852
United States
Email: anos@mail.nih.gov
Phone: 301-496-7057
Fax: 301-402-0220
Ref No: 230
Updated: 02/2011