Circulating tumor cells (CTCs) are a marker of cancer, and the ability to count live, individual CTCs in the bloodstream can help doctors determine the severity of a cancer, as CTC density in the blood is linked to the progression of the disease and patients' likelihood of survival. Scientists from Peking University (China) have devised a microfluidic chip that can quickly and efficiently segregate and capture live CTCs from a patient's blood, with potential applications for cancer screenings and treatment assessments. The ability to count live, individual CTCs in the bloodstream can help doctors determine the severity of a cancer, since CTC density in the blood is linked to the progression of the disease and patients' likelihood of survival. The study authors submit that: “The work here indicates that our system can be developed for use in cancer screening, metastatic assessment, and chemotherapeutic response and for pharmacological and genetic evaluation of single [circulating tumor cells].”
Peitao Lv, Zhewen Tang, Xingjie Liang, Mingzhou Guo, Ray P.S. Han. “Spatially gradated segregation and recovery of circulating tumor cells from peripheral blood of cancer patients.” Biomicrofluidics, 6 June 2013.
A spouse's social network quality may influence blood pressure in the other spouse.
Chinese scientists devise a microfluidic chip that can quickly and efficiently segregate and capture live circulating tumor cells (CTCs) from a patient's blood.
High-intensity interval training (HIIT) provides cardiovascular benefits, among women.
Asthma sufferers who are frequently exposed to heavy traffic pollution or smoke from wood fire heaters experience a significant worsening of symptoms.
Volunteering may improve your mental health and help you live longer.
Higher debt associates with worse health, among young Americans.
Daily consumption of sea buckthorn berries and its extracts may promote metabolic and heart health, among overweight women.
To optimize stem cell therapies, UK researchers develop gold nanoprobes that help to enable cell identification on a molecular scale.
Among cancer survivors experiencing sleep difficulties, yoga helps to improve sleep quality.
Moderate levels of added sugar reduce survival and compromises fitness and reproduction, in a lab animal model.
Molecular robots hone in on specific populations of human cells, directing therapeutic drugs to specific targets.
Saliva from people who use cell phones as little as eight hours a month show increases in markers that correlate to potential cancer risk.
Concept utilizes nanoparticles that concentrate and expand in the presence of higher acidity found in tumor cells.
Large-scale European study suggests that long-term exposure to low-level air pollution may increase the risk of lung cancer, and adenocarcinoma in particular.
Consuming a modest amount of walnuts may confer protective effects against prostate cancer, suggests data from a lab animal study.
Increased intakes of omega-3 polyunsaturated fatty acids may cut a woman’s risk of developing breast cancer by up to 14%.
Higher blood levels of Vitamin B6 associate with less damage to DNA, among men.
Chlamydia trachomatis can cause mutations in the host DNA, thereby leading to the development of cancer.
The invisible remains of cigarette smoke that deposit on carpeting, clothing, furniture and other surfaces may be a major cause of significant genetic damage in
Exposure to low doses of the synthetic compound bisphenol A (BPA) is linked to increased risk of prostate cancer in human stem cells.
Tip #192 - Stay Connected
Researchers from the University of Chicago (Illinois, USA) report that social isolation may be detrimental to both mental and physical health. The team analyzed data from the National Social Life, Health, and Aging Project, a nationwide US study involving 3,000 men and women, ages 57 to 85 years. They arrived at three key findings regarding the relationships between health and different types of isolation:
• The researchers found that the most socially connected older adults are three times as likely to report very good or excellent health compared to those who are least connected, regardless of whether they feel isolated.
• The team found that older adults who feel least isolated are five times as likely to report very good or excellent health as those who feel most isolated, regardless of their actual level of social connectedness.
• They determined that social disconnectedness is not related to mental health unless it brings feelings of loneliness and isolation.
Separately, Rush University Medical Center (Illinois, USA) researchers studied 906 older men and women, testing their motor functions (including grip, pinch strength, balance, and walking) and surveying their social activity, for a period of 5 years. Those study participants with less social activity were found to have a more rapid rate of motor function decline. Specifically, the team found that every one-point decrease in social activity corresponded to an increase in functional aging of 5 years, translating to a 40% higher risk of death and 65% higher risk of disability.