Long-Term Use of Blood Pressure Medications that Promote Sun Sensitivity May Increase Risk of Lip Cancer in Non-Hispanic Whites
Posted Aug 07 2012 5:17pm
Long-term use of commonly used blood pressure medications that increase sensitivity to sunlight is associated with an increased risk of lip cancer in non-Hispanic whites, according to a Kaiser Permanente study that appears in the current online issue of Archives of Internal Medicine.
Funded by the National Cancer Institute, the study found that photosensitizing antihypertensive drugs such as nifedipineand hydrochlorothiazide were associated with cancer of the epithelial cells known as squamous cells — which are the main part of the outermost layer of the lips and skin.
Researchers compared 712 patients in Northern California with lip cancer to 22,904 people in a control group and found that the risk of squamous cell lip cancer was higher for those with long-term use of photosensitizing blood pressure medications.