A recent study has been released in The Annals of Neurology with good news. Yet another cause of peripheral neuropathy has been identified. Ideopathic small fiber neuropathy, commonly said to have an "unknown cause" has now been found to have a genetic mutation in 28.6% of cases. The Neuropathy Doctor has given a brief explanation of this new finding and a little information about how it will cause nerve discomfort.
This gene activates a sodium channel in the small diameter nerves that causes hyperexcitable nerves or nerves that "over-react" to simple stimuli. In neuropathy this is commonly seen as electrical shocks, stabbing pain, burning pain or even "pins and needles". Since this mutation has been identified, hopefullly in the near future treatment options will also be found.