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How Bad is LDL Cholesterol? (continued)

Posted Jan 23 2009 3:45pm

If LDL cholesterol level predicts heart disease then persons with low LDL should be better off than persons with high LDL. Here is what some Norwegian doctors did:

They simply selected sequential patients with LDL cholesterol scores below 2.7mmol/l. . . . They ignored all people with LDL concentrations from 2.7 to 4.5mmol/l but did enroll all people with an LDL >4.5mmol . . .  So they then had two groups of people, those at catastrophic risk of LDL-blocked-arteries and those with [very] little LDL . . . They did the scheduled angiography and checked how many patients had >70% blockage of at least two coronary arteries in each group.

Guess what: LDL cholesterol doesn’t matter. They recruited 47 patients with low LDL-C, of whom 21 had significant CAD. They got 46 high LDL-C patients, of whom 24 turned out to have CAD.

Thanks to Dave Lull.

How bad is LDL cholesterol?

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