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Hormone Replacement Therapy Linked to Increased Lung Cancer Risk

Posted Mar 04 2010 3:11pm

New study finds prolonged use of HRT increases incidence of lung cancer by about 50 percent

Women aged 50 to 76 who take estrogen plus progestin may have an increased risk of lung cancer, according to a new study published in the pre-print online edition of the Journal of Clinical Oncology.

Although the risk is “duration-dependent,” with women taking HRT for 10-plus years at greatest risk of developing lung cancer, an acceptable length of HRT has yet to be determined, the researchers report.

While the risk of developing lung cancer for women using estrogen plus progestin HRT 10 years or longer was approximately 50 percent more than women not using HRT, this risk is actually quite small compared to the risk from smoking.

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