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HIV Drugs Interfere With Blood Sugar, Lead To Insulin Resistance

Posted Nov 23 2010 5:06pm

The same powerful drugs that have extended the lives of countless people with HIV come with a price — insulin resistance that can lead to diabetes and cardiovascular disease.

Now, researchers at Washington University School of Medicine in St. Louis have determined why that happens. Their research shows that HIV protease inhibitors directly interfere with the way blood sugar levels are controlled in the body. This leads to insulin resistance, a condition that occurs when the body produces enough insulin but doesn’t use it properly.

This confirmation provides the potential to develop safer antiviral drugs.

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