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High-Dose Vitamin E Increases Prostate Cancer Risk

Posted Oct 11 2011 6:19pm

High-dose vitamin E supplements increase the risk of prostate cancer, results of a large clinical trial show.

The study’s findings, published Oct. 12, 2011, in the Journal of the American Medical Association, are based on an updated review of data from the Selenium and Vitamin E Cancer Prevention Trial (SELECT). More than 35,000 men age 50 and older were enrolled in the study to determine whether selenium and vitamin E, either alone or in combination, can lower a man’s risk for prostate cancer.

Among the men who took high-dose vitamin E daily, the researchers found a 17 percent increase in prostate cancer, compared with men who took a placebo.

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