A gene that governs ovulation -- the release of a mature egg from a female's ovary -- has been identified by researchers in Canada and France, Canada's Globe and Mail newspaper reported Friday.
The finding means that a drug affecting the gene could be developed to treat infertility caused by a female's inability to ovulate. Conversely, a genetically based contraceptive could stimulate the gene to prevent ovulation, the newspaper said.
Researchers at the University of Montreal and at the Université Louis Pasteur deleted the gene, called Lrh1, from mice. This stopped ovulation, affected hormone cycles, seemed to prevent eggs from maturing, and stopped them from leaving the ovaries, the Globe and Mail reported.
The next step, the scientists said, is to collect ovarian cells from fertility clinics to see if these cells contain a defective Lrh1 gene.
The research is published in the current issue of the journal Genes and Development.
Youth All-Terrain Vehicles Recalled
About 144 all-terrain vehicles designed for children are being recalled because they lack a number of safety features, the U.S. Consumer Product Safety Commission says.
The ATVs, produced in China, were distributed across the United States by the SunL Group of Irving, Texas. They were sold from May 2005 to March 2007 for $400 to $500.
Intended for children aged 12 to 15, the recalled model SLA90 lacks a number of features, including front brakes, a manual fuel shut-off, and padding to cover sharp edges on the handlebars, the CPSC said.
Consumers should stop using the vehicles immediately, and contact SunL to learn how to obtain a full refund. The toll-free number is 866-355-0497.
Global Warming Poses Major Health Threat: EPA
An increase in heat waves, more powerful hurricanes, disease, and depletion of drinking water are likely in the coming decades as a result of global climate change, the U.S. Environmental Protection Agency warns in a new report.
"It is very likely" that more people will die from weather conditions such as heat waves, said the report, issued Thursday. The elderly, economically disadvantaged, and inner-city dwellers are most at risk, according to report data cited by the Washington Post.
Ironically, the EPA decided last week not to immediately assume authority over carbon dioxide and other greenhouse gas emissions under the Clean Air Act, the newspaper said.
"Today typifies the climate-change schizophrenia in the Bush Administration," said Rep. Edward Markey (D-Mass.), who chairs the House Select Committee on Energy Independence and Global Warming. "On one hand, government scientists are saying that global warming poses grave threats to our health and our welfare, and, on the other hand, there are White House political hacks following the oil industry's bidding to do nothing."
The newspaper quoted White House spokesman Tony Fratto as saying that EPA administrator Stephen Johnson made the decision about greenhouse gasses on his own.
U.S. Set Birth Record Last Year
There were more births in the United States last year than at any time in the nation's history, according to a National Center for Health Statistics report cited by the Associated Press.
Some 4,315,000 babies were born in 2007, agency demographer Stephanie Ventura said.
While that amounts to roughly 15,000 more births than during the peak baby-boom year of 1957, Ventura discounted the notion of a new baby boom. She noted that there were far fewer women of childbearing age 50 years ago.
"What this really reflects is that the population has grown so much in the United States, so you naturally expect more births," she said. "It's hard to call this a baby boom at this point."
HIV Vaccine Trial Canceled Over Possible Volunteer Risk
The sponsors of a planned human trial for an AIDS vaccine canceled the project Thursday, saying they doubted the vaccine's effectiveness and noted that the trial could actually put volunteers at risk of acquiring HIV, The New York Times reported.
The trial, called PAVE (Partnership for AIDS Vaccine Evaluation), was to be conducted by a consortium of U.S. agencies and private organizations. It was to have begun enlisting 8,500 volunteers last October to evaluate a vaccine developed by the National Institute of Allergy and Infectious Diseases.
The trial was shelved, however, after a similar vaccine developed by Merck & Co. failed to prevent the infection and lower blood levels of HIV among people who had already acquired the AIDS-causing virus, the newspaper said.
Data from the Merck vaccine trial also suggested that the shot might have increased some users' risk of acquiring an HIV infection.
Attempts to create an effective HIV/AIDS vaccine have been in the making for more than 25 years, and developing one still appears years away, scientists told the Times.