Fox Chase Researchers Find that Aspirin Reduces the Risk of Cancer Recurrence in Some Prostate Cancer Patients
Posted May 02 2011 6:19pm
Some studies have shown that blood-thinning medications, such as aspirin, can reduce biochemical failure––cancer recurrence that is detected by a rising prostate-specific antigen (PSA) level––the risk of metastasis and even death in localized prostate cancer. These studies, although very telling, have all emphasized the need for more data. Now, with researchers at Fox Chase Cancer Center having concluded the largest study on this topic, and there is substantial data suggesting that aspirin improves outcomes in prostate cancer patients who have received radiotherapy.
A team led by Mark Buyyounouski, MD, MS, a radiation oncologist at Fox Chase, examined a database of over 2000 prostate cancer patients who underwent radiotherapy at Fox Chase between 1989 and 2006 and found that aspirin use lowers the risk of cancer recurrence. The scientists will present their findings on Sunday, May 1 at the 93rd Annual Meeting of the American Radium Society.
The team found that the 761 men who took aspirin at or after the time of radiotherapy were less likely to experience biochemical failure––as indicated by the levels of PSA––than were the 1380 men who didn’t take the drug.