Health knowledge made personal
Join this community!
› Share page:
Search posts:

Exercise Helps to Prevent Brain Changes Due to Inflammation

Posted Sep 09 2011 10:19pm
Posted on 2011-09-08 06:00:00 in Alzheimer's Disease | Exercise | Inflammation |
Exercise Helps to Prevent Brain Changes Due to Inflammation


Previously, research has shown that exercise after brain injury can help the repair mechanisms. This new study shows that exercise before the onset of damage modifies the brain environment in such a way that the neurons are protected from severe insults. Jean Harry, from the National Institute of Environmental Health Sciences (North Carolina, USA), and colleagues used an experimental model of brain damage, in which mice are exposed to a chemical that destroys the hippocampus, an area of the brain which controls learning and memory. The team observed that mice that were exercised regularly prior to exposure produced interleukin-6 in the brain, which dampened the harmful inflammatory response to this damage, and prevented the loss of function that is usually observed. This research helps to elucidate how exercise could be used to affect the path of many human conditions, such as neurodevelopmental disorders and neurodegenerative diseases. In addition, as a chemical model of neuronal damage was used, it also raises the possibility that exercise could offer protection against the potentially harmful effects of environmental toxins. 


Jason A. Funk, Julia Gohlke, Andrew D. Kraft, Christopher A. McPherson, Jennifer B. Collins, G. Jean Harry.  “Voluntary exercise protects hippocampal neurons from trimethyltin injury: Possible role of interleukin-6 to modulate tumor necrosis factor receptor-mediated neurotoxicity.”  Brain, Behavior, and Immunity, Volume 25, Issue 6, August 2011, Pages 1063-1077.

View Current Anti-Aging Newsletter!
Four behaviors characteristic of the anti-aging lifestyle markedly slash the risks of death.
Watching TV for an average of six hours a day may shorten a person’s life expectancy by almost five years.
Regular exercise may help prevent inflammation-related brain damage characteristic in Alzheimer’s Disease.
Due to disease-related inflammation, people with rheumatoid arthritis (RA) are at an increased risk of death due to cardiovascular disease.
Adding various spices to a plain meal can significantly reduce post-meal insulin and triglyceride levels.
In a cancer treatment breakthrough University of Pennsylvania (US) researchers have shown remissions among a small groupp of lymphocytic leukemia (CLL) patients
Consuming red meat – especially processed types (such as deli meats, bacon, and sausage) – raises a person’s risk of developing type-2 diabetes.
Spanish team reveals that a cocoa-rich diet significantly reduces the activation of NF-kappaB, a protein that plays a key role in the inflammatory process.
Northwestern University (US) team reports that being physically active is one of best ways people with arthritis can improve their health.
Elderly women who suffer from sleep apnea are about twice as likely to develop dementia in the next five years.
16–18 Stem Cell Fellowship:
Module II
A4M Board Certification Exams offered at this venue

21–23 Stem Cell Fellowship:
Module III
8–10 Stem Cell Fellowship:
Module IV
A4M Board Certification Exams offered at this venue
International Events

Post a comment
Write a comment:

Related Searches