Health knowledge made personal
Join this community!
› Share page:
Go
Search posts:

Exceptional Survivors who work with aboriginal healers

Posted Feb 19 2008 6:09pm
Here's my paper on this topic, to be published in the Journal of Complementary and Alternative Medicine.



Narratives of Exceptional Survivors who work with Aboriginal[*] Healers

Lewis Mehl-Madrona, MD, PhD
Departments of Family Medicine and Psychiatry
University of Saskatchewan College of Medicine
Saskatoon, SK, Canada

Address communication to Dr. Mehl-Madrona at narrativemedicine@gmail.com or West Winds Primary Health Centre, 3311 Fairlight Dr., Saskatoon, SK S7M 3Y5, Canada, telephone 306-655-4249 and fax 306-655-4894.

Abstract

The commonalities are described of 47 people who sought traditional aboriginal healers for help with their cancer. All has 10% or less chance of survival at 5 years given the site and stage of their cancer from actuarial table calculations. They were compared to a similar group of people also working with aboriginal healers who did not survive past 5 years. Narratives were obtained from the people before and after their work with the healer. These stories were enriched through interviews with family members, friends, health care providers, and the healers themselves, whenever possible. Panels of naïve medical students, graduate students, patients, and health care providers were used to evaluate the stories and to pick themes that consistently emerged (dimension analysis). Once stable dimensions emerged, scenarios were developed to rate patients along these dimensions from “1” to “5”. New panels did the ratings with at least three panels of three people per narrative. Comparisons were made between these two groups of people and differences emerged on the dimensions of Present-centeredness; Forgiveness of others; Release of blame, bitterness, and chronic anger; Orientation to process vs. outcome; Sense of Humor; Refusal to accept death as immediate prognosis; Plausible (to the patient, his or her family, and the healers) explanation for why he or she got well, including a story reflecting a belief about how he or she can stay well; Supportive community who believes in the person's cure and protects the person from outsiders who think the person will die; People experience a quantum change, in which a major improvements in self-esteem and quality of relationships occurs; and Spiritual transformation. The two groups of people reported equal increases on the dimensions of Sense of Meaning and Purpose and Faith and Hope, which may be intrinsic to the style of healing of aboriginal elders.
Gotay et al. (2004) have defined exceptional survivors as people who have survived at least 5 years with less than 25% actuarial probability of doing so, given their site and stage of cancer at diagnosis. She compared exceptional survivors of cancer to non-exceptional survivors with the same cancers and sites (but with greater than 25% actuarial probability of living 5 or more years), and with normative data for the instruments used from the general population. She found that both types of survivors had high levels of well-being compared to the normative populations, cancer survivors exhibited higher levels of coherence and resiliency, but not optimism with few differences between the two types of survivors.
Widespread interest exists in “exceptional survivors” and how they come to be so. The conventional oncological argument holds that they are merely the end of the bell-shaped curve and are not different psychologically or spiritually from any other survivor. O’Regan and Hirshberg (1993) documented more than 1000 cases in which cancer apparently went into spontaneous remission. Some of these fascinating cases and others were described in a best selling book two years later (Hirshberg & Barash, 1995). While it is difficult for some to understand how non-medical healing might affect an organic disease like cancer, these intriguing reports suggest this possibility. Survival is not necessarily of more importance than quality of life, but clear demonstrations of such an effect might compel us to consider changing our management of cancer patients. The potential of the mind to influence the course of cancer is of theoretical interest, and any effects might apply to other chronic diseases.
Work with animal models has clearly shown a relationship between psychological determinants and tumor growth (La Barba, 1970: Sklar and Anisman, 1981: Visintainer et all, 1983). Research on the relationship of human personality to cancer has not yielded clear correlations (reviewed by Garssen and Goodkin, 1999). Prospective studies have implicated a number of possible risk factors, the most consistent finding being repression of emotion or depression (Shekelle et al, 1981; Daftore et al,, 1980: Hislop et al. 1987: Jensen, 1987: Kaasa et al.: 1989 Temoshok: 1987; Gross, 1989), a conclusion disputed by Kreitior et. al (1993). Other, larger studies have failed to show a connection between cancer and depression (Kaplan and Reynolds, 1988: Hahn and Petifti, 1988; Zonderman et al., 1989). Factors which some have found to be protective include social support (Eiii et al., 1992; Waxier-Morrison et al., 1991; Maunsell et al., 1995) disputed by Funch et al. 1983 Cassileth et al,. 1988), greater expression of distress (Derogatis et al 1979), smaller numbers of severe or difficult life events (Ramierez 1989), and fighting spirit" (Pettingale et al, 1985). Other investigators, however, have not found these relationships (Cassileth et al., 1988. Jamison et al., 1987). Fighting spirit, measured psychometrically, did not affect survival in a recent analysis of 578 patients done by Watson et al., (1999).
Evidence from controlled trials of psychological interventions is mixed. At the time of writing, there are 9 published trials with randomized, case control or sequential cohort designs. Four showed a positive effect of an intervention on survival. In the best-known of these, Spiegel et al. (1 989) demonstrated an 18 month average prolongation of life in women with metastatic breast cancer who attended a weekly support group for up to 1 year. However, the control group in this experiment may have been anomalous, since as pointed out by Fox (1998), its members died more rapidly than similar populations of patients who were not in therapy. Richardson et al., (1990), using a sequential cohort design, found significant effects of a psychological intervention in patients with hematological malignancies. Fawzy et al. (I 993), in a randomized trial, similarly demonstrated a significant survival advantage to patients with malignant melanoma who had taken a brief, group, psycho-educational course 6 years before. Ratcliffe et al., (1995) found a small but marginally significant difference in survival of patients with lymphoma who received training in relaxation compared with randomized controls who did not.
All trials specifically designed to test effects on survival have given negative results. The first of these, by Linn et al (1982), was a randomized comparison of the lifespan of patients with a variety of late-stage cancers who either received or did not receive individual counseling (for an unspecified time). The second, by Morganstern et al. (1984), was a case controlled study, which showed a non-significant trend in favor of longer survival in patients in group therapy. Two more recent studies were RCT's using interventions simiIar to those of Spiegel and of Fawzy, respectively. Cunningham et al., (1988) gave 35 sessions of group supportive and psycho-educational therapy to women with metastatic breast cancer: these subjects did not live significantly longer than controls. Edelman et al.(l 999) used a brief, 11 session, cognitive behavioral intervention which also failed to prolong the life of patents with metastatic breast cancer, by comparison with controls. One further published study, not designed to test for survival and with a weaker design, has also given negative results in a post hoc analysis (Ilnyckyl et al., 1994).
Further RCTs may eventually yield a consensus about the mean effects of psychotherapy on survival, although adequate experiments are likely to be large and expensive, especially since we don't know how to stratify subjects for such trials. We don't know the characteristics of patients who are susceptible to remarkable healing, psychological, social, or genetic. Others have argued that qualitative data may be needed to detect a mind/cancer link (Morris et al., 1985; 1992; Temoshok et al., 1985; Temoshok, 1987; Somerfield. and Curbow, 1992). This qualitatively based approach, although labor intensive, has a further advantage, in that it facilitates assessing complex constellations of variables (e.g., " Application to self help work," which requires more than just listing behaviors, e.g., the individual's dedication or intensity of self help work must also be captured).
The study of exceptional survivors could also shed some light on possible connections between efforts at mental self help and cancer remission or prolonged survival and has a literature (Ikemi et al, 1975; Kennedy et al, 1976; Achterberg et al, 1977; Roud, 1986; Pennington, 1988; Huebscher, 1922a and b, Berland, 1995). The picture emerging from these studies is consistent with findings from Cunningham's (2000) pilot work; patients who lived longer than expected were flexible, self-motivated, and usually reported significant changes in behaviors and attitudes. However, in all these accounts, patients were selected retrospectively, so that there was no way of knowing how many patients showed similar characteristics but failed to survive. All have other serious methodological defects as well: medical documentation was almost nonexistent, and in some cases subjects who had medically curable cancers were included? Most collected data was from a single interview only, usually years after recovery; and only 2 used standard qualitative methods. In recent years, there have been a number of randomized, controlled trials, which have yielded mixed results on psychological interventions and cancer survival In particular, all trials specifically designed to test the hypothesis that psychological change prolongs survival have so far given negative results, suggesting that any effect that exists is likely to be small. Yet there is an accumulation of clinical experience pointing to the existence of a minority of cancer patients who make strong efforts to help themselves psychologically and appear to live longer than expected (e.g., lkemi et al, 1975: Kennedy et al. 1976; Achterberg et al. 1977; Meares 1980; Newton, 1982; Roud, 1986; Berland, 1995). How can we reconcile this divergence between the inconsistent results of these trials and the clinical observations, or are the latter simply the result of therapists' desire to attribute efficacy to their interventions?
While there is still little known about the detailed mechanisms of cancer regulation, we can put forward a logical hypothesis. Any effects of the mind would necessarily act through neurological or endocrine pathways on biological response modifiers, such as immune mechanisms or cytokine activity that might, in turn, influence tumor progression (Schipper et al.. 1995). It would follow that the size of effect on the regulators of cancer growth would reflect the degree of change at higher levels of the pathway, and ultimately, the degree of initial psychological change. We might therefore expect to see a relationship between the extent of work and change patients exhibit, and effects on tumor retarding mechanisms, and hence lifespan.
This line of reasoning leads to a conclusion that is potentially important for studies on the possible prolongation of life by psychological therapies in cancer patients. If only a small proportion of the patients in therapy group become strongly involved in trying to help themselves psychologically (as we observe), and theirs are the only lives substantially prolonged, this effect may be "diluted out" when group means are calculated. An RCT would thus need to be large to produce a reliable treatment effect (all so far published have been small).
In order to detect any sub-population of patients whose psychological work leads to longer survival, we need to ask: "is the way patients respond to therapy or treatment of any kind, particularly in their degree of involvement with proposed self-help strategies, related to duration of survival?" To know what to ask, we need to find long-term survivors who attribute their survival to non-medical means and who would not be predicted to survive on medical grounds alone.
Because of the author’s position as a connector between traditional aboriginal healers and people who wished to consult traditional aboriginal healers, his clinical practice provided a unique opportunity for accumulating stories of exceptional cancer patients who used aboriginal healing as part of their path to wellness. This paper reports on some of these patients.

Methods

Since 1980, the author has been helping people who wish to work with traditional healers to find them. He has also done his own “neo-traditional” healing work in the manner of traditional healers, but in a more modern context (Mehl-Madrona, 1998, 2003, 2005). Stories from this work are not included in this series. Rather, the author reports upon stories collected from patients in his practice for whom his primary role was supportive and to facilitate the patients finding a traditional healer. Forty-seven stories were selected of patients who met the definition of exceptional survivor. These people’s stories were matched (for comparison purposes) with 47 patients who had cancers of the same site and stage, but who did not live 5 years.

A more stringent definition of exceptional patients was used than provided by Gotay et al. (2004) in that people included had less than 10% actuarial likelihood of surviving 5 years given the site and stage of their cancer at diagnosis. This prediction was confirmed by three oncologists. Stories from the people themselves were enriched by the parallel accounts of family members and friends. Whenever possible, local health care providers were also contacted for further details of the story. Some of these exceptional patients were legendary in their community, often called upon as examples of healing.

Qualitative studies such as these cannot speak to the prevalence of such patients. When the author gives lectures, he finds that 25% to 40% of audiences know at least one person who has had a "miracle cure" from cancer. The author suspects that the so-called "outliers" --which these patients clearly represent -- are more common than conventional medicine expects. Outliers may be especially more common outside mainstream culture, where beliefs in the wisdom of conventional physicians are not so strong. The purpose of this paper is to commonalities among these patients, understanding that this methodology provides no support for the argument of causality.

Questions asked to compile people’s stories included (and were not limited to):
1)Why do you think you developed cancer?
2)Do you think working with the medicine man (woman) helped you?
3)What do you think allowed you to get well?
4)What did the healer tell you to do?
5)What did the healer do with you?
6)Did you think it would work?
7)How do you explain your wellness?
8)What do members of your family think?
9)What do members of your community think?
10) What was your prior experience with Native American spirituality and ceremony before your work with the healer?
11) What has been your past exposure to spirituality? Religion? Ceremony?
12) How would you describe your past spiritual experiences? Have they been positive, neutral, or negative?
13) What role does spirituality and/or religion play in your life? What is your religion? How do you define spirituality?
14) Have you had any extraordinary or unusual spiritual experiences?
15) Have you ever had a period of intense suffering? When? How did you get over it?
16) When people talk about spiritual transformation, what do they mean?
17) Have you ever had a spiritually transforming experience? How about a peak experience? When was that? What happened?
18) Do you have a daily spiritual practice? What do you do?
19) What are your important relationships? Who do you love? Who loves you? Do you feel loved?
20) What do people mean when they talk about spiritual growth? In what areas would you like to grow?
21) Have you had any particular sensory experiences that seemed remarkable (visual, kinesthetic, olfactory, smell, etc.)?
22) How did your mental state change from when you were first diagnosed until today?
23) How did your sense of self change from diagnosis until now?
24) What did you think the healer was intending to do when he or she worked with you?
25) What was your favorite part of your work with the healer? Your least favorite part?
26) Did your sense of the sacred and what is sacred change? If so, how? How much?
27) Did your sense of how to pursue the sacred (your own particular path toward the sacred) change? If so, how? How much?

All people were followed at least five years after diagnosis or until the time of death, though in an important sense, the focus of this paper is upon the stories told and not the actual people themselves, for the raters had no access to the people, only to their stories.

Qualitative Methods.

(a). Analytic Method: Schatzman’s (1991) grounded method of “dimensional analysis,” as interpreted by Kools, et al. (1996) and Cunningham, et al. (2000) was used. The first 5 to 8 stories were used to develop a “vocabulary” of concepts or categories encompassing issues important to subjects from interviews. The key process in dimensional analysis is naming the main components and describing their various attributes (“dimensionalizing”). The goal is to cluster the final number of categories into a smaller number of dimensions. Prior knowledge is acknowledged as an important part of theory building in dimensional analysis, unlike the “blank slate” approach assumed in some grounded methods (Strauss & Corbin, 1990).

The author wished for more of a “Wittgensteinian ordinary people” rating. Thus, stories were distributed at retreats, trainings, and workshops (with Proper Nouns changed so that the people could not be identified). Participants were invited to read the stories and identify what they thought were the major themes present. We discussed methods and prior work that had been done in the field, since we did not believe anyone could actually be a blank slate. Assessment was done by groups of 3-5 people with each story having at least three groups rate them. The work was done by cancer patients, health practitioner students, and health practitioners meeting in workshops or retreats as part of the learning about the mind and cancer process. Twenty-four such sessions were held. The twelve categories listed below appeared at least 70% of the time in different sessions and appeared stable. Other categories which appeared less than 70% of the time are not reported in this paper, though some were quite interesting. Consensus was reached in each session about the categories that the entire group believed to be relevant.

(b). Rating of categories: Once 12 stable dimensions had emerged, the same procedure was used to develop a quantitative rating of, following examples in the text on qualitative data analysis by Miles & Huberman (1994). For each of the themes that emerged and that were suitable for quantitation, scenarios were written describing the patterns of behavior and thought that qualified for a score of “1”, “3”, or “5” on a five-point scale. The scenarios were developed in the same manner as the dimensions. Ratings of “2” and “4” were applied when data fell between scenarios. Once consensus had been reached on rating scenarios, then they were applied in future sessions by participants until all stories had been rated on all 12 dimensions with at least three groups rating the stories at least three times.

(c). Reliability and validity of the process: Reliability: Once scenarious were developed, inter-rater reliability by members of each team remained above 0.7 for each dimension and between teams above 0.75. This happened readily without training and was related to the scenarios being clear and being developed by ordinary people over multiple passes. The rating scenarios are available upon request.

Results

The modal age range of the patients interviewed was the fifth decile of life (ages 40 to 49; Table 1). Patients came from a wide range of cancers (Table 2).

The theoretical categories that emerged as potential candidates for explanatory factors for these patients dramatic outcome are:

1.Present-centeredness.
2.Forgiveness of others.
3.Release of blame, bitterness, chronic anger.
4.Acceptance of death.
5.Humor.
6.Reduced attachment to outcome versus commitment to a process of life change, with resulting increase in sense of life-meaning and dignity.
7.Faith and hope in something.
8.Refusal to accept death as immediate prognosis.
9.Plausible (to the patient, his or her family, and the healers) explanation for why he or she got well, including a story reflecting a belief about how he or she can stay well.
10.Supportive community who believes in the person's cure and protects the person from outsiders who think the person will die.
11.People experience a quantum change, in which a major improvements in self-esteem and quality of relationships occurs.
12. Spiritual transformation
Review of the life stories of 50 cancer patients who died, did not reveal anywhere near the same degree of these qualities, lending possibility to the hypothesis that these may be attributes of the "states of mind" that are most compatible with "miracle cures."

Table 1. Age Ranges of people finding "miracle cures."

Age Range Number of Exceptional
Survivors
20 - 29 12
30 - 39 23
40 - 49 30
50 - 59 29
60 - 69 2
70 - 79 1
80 - 89 2


Table 2. Summary of Cancer Patients:
Number Ave. Years Ave. Years to Death
Type of Cancer Patients Disease Free Non-survivors
Lymphoma 4 9 3
Metastatic Breast Cancer 12 9 3
Prostate Cancer 4 5 3
Metastatic Ovarian Cancer 4 17 1
Malignant Melanoma 1 5 4
Colon Cancer 9 14 4
Brain Cancers 7 6 1
(glioblastoma, astrocytoma)
Esophageal Cancer 1 13 2
Lung Cancer 2 11 1
Pancreatic Cancer 1 21 1
Multiple myeloma 1 6 4
Non-Hodgkin's Lymphoma 1 12 3

Total Cancers 47


Table 3. Comparisons between Exceptional Survivors and Non-Survivors for Rating Scenarios of Identified Dimensions in their stories (* denotes statistical significance of at least p < 0.05 and standard deviations are included in parentheses):

Identified Dimension Rating for Rating for
Exceptional Survivors Non-Survivors
1.Present-centeredness.* 3.8 (0.8) 2.8 (0.9)
2.Forgiveness of others.* 4.1 (0.9) 2.0 (0.4)
3.Release of the past.* 2.7 (0.7) 1.6 (0.6)
4.Process orientation.* 4.4 (2.0) 3.4 (2.5)
5.Humor.* 3.4 (0.8) 1.9 (0.3)
6.Life-meaning and dignity. 3.6 (1.0) 3.2 (0.5)
7.Faith and hope. 3.0 (0.9) 3.1 (1.0)
8.Refusal to accept death.* 4.3 (0.3) 3.3 (0.7)
9.Plausible explanation.* 3.2 (1.0) 1.9 (1.1)
10.Supportive community.* 3.1 (0.9) 2.0 (0.9)
11. Quantum Change.* 3.0 (0.8) 1.8 (1.0)
12. Spiritual Change.* 3.2 (1.0) 1.8 (0.8)

Dimensions were identified that were different between the two groups. Two dimensions were not different among the two groups and are probably at the heart of aboriginal healing regardless of outcome – meaning and dignity and faith/hope. The survivors seemed more present-centered, forgiving, disconnected from their past, and humorous. They had more plausible explanations to both self and community for why they healed, had more supportive communities, changed more, and had more spiritual change. That naïve raters could identify these differences is important.

Conclusions

These results are preliminary and constitute more of a pilot study to guide further investigation than a definitive answer to the mind-body problem in cancer. These findings suggest that raters can read stories and identify differences between exceptional survivors and non-survivors, all of whom were working with traditional aboriginal healers. This suggests that exceptional survival could involve a change in these attributes that could be called healing and could be non-random, though the frequency cannot be assessed. Further research should be undertaken to determine if stories and their qualitative analysis could be used prospectively to identify longer-term survivors and discriminate them from shorter term survivors.

These data provide preliminary support for the argument that states of mind/relationship are associated with lengthened survival. The actual dimensions identified, however, may not be as important as the gestalt impressions which the raters made and assigned to the dimensions as the best way they new to convey their impressions. In other words, the stories may contain more richness that the raters intuitively used than the dimensions identified would suggest.

Belief in the plausibility of the explanation for survival seemed particularly important. Roberts (1983, 1993, 1995) concluded that if both patient and physician believed in the effectiveness of a treatment, outcomes closely approximate one third excellent results, one third good results, and one third poor results. Belief in treatment and plausibility of the story about how the cure occurred, are both important preliminary proposed variables for the state of mind associated with healing. Roberts studies of biologically ineffective treatments in which patients and doctors believed showed combined average reported effectiveness of 40% excellent results, 30% good results, and only 30% poor results, for a mean total of 70% positive outcomes.

Miller and deBaca (1994) have proposed that quantum change is important for dramatic physiological changes. Quantum changes are sudden, permanent, major shifts that sweep through the whole life of a person. Native American healing philosophy teaches that such quantum changes are often necessary to change the tide in a patient who is deteriorating. Participation in ceremony can be one catalyst of quantum change.

The faith and hope of most persons covered in this study rested in spiritual resources and supernatural beings, along with their faith in the skill of the traditional healer. Spiritual healing has remained an untapped resource in our health care even though research has begun to document its effectiveness (Larson & Larson, 1994).

One could call the treatment that took place, spiritual healing. Spiritual approaches are not completely foreign to the American mainstream. They are frequently used in the treatment of addiction disorders. Among patients suffering from depression, those receiving a spiritually-oriented therapy had better scores on measures of post-treatment depression and life adjustment than did those whose treatment did not include a religious content (Propst et al, 1992). Patients' religious commitment has been shown to improve their treatment outcomes and recovery rates, decreasing their length of stay in hospitals and reducing the need for costly drugs or follow-up care. Recovering schizophrenics who attended church or were given supportive aftercare by religious caregivers had lower overall rates of rehospitalization (Chu & Klein, 1985; Katkin et al, 1975). Patients with hip fracture who are religiously committed have been found to suffer from less depression after their injury and recover more rapidly than patients with lower levels of religious commitment (Larson & Milano, 1997).

Among 232 patients undergoing elective heart surgery, six months later, 9% had died (Oxman et al, 1995). None of the 37 who described themselves as deeply religious before surgery had died. Whereas only 5% of those who attended church as infrequently as every few months died after the operation, 12% of those who rarely or never attended church died during the same 6 months after their operation.

Thus, traditional spiritual healing could have played a role in helping these people to become exceptional survivors. Further study is indicated.

References

Aaronson, N., Abmedzai.S., Bergman, B., Bullinger, M., Cull, A., Duez, N.J. et al. (1993. The European Organization for Research and Treatment of Cancer QLQ-C30. A Quality of life instrument for use in international clinical trials in oncology. J. Of the Nat. Can. Inst., 85(5), 365-376.Achterberg J., Mathews-Simonton S., Simonton O.C. (1977). Psychology of the exceptional cancer patient: A description of patients who outlive predicted life expectancies. Psychotherapy. Theory Res. Pract. 14, 416-422Anderson, B.L. (1992). Psychological Interventions for cancer patients to enhance the quality of life. J Consult Clin. Psychol., 60, 552-568.Berland, W. (1995). Unexpected cancer recovery: Why patients believe they survive. Advances J. of Mind-Body Health. 11, 5-19.Bjordal, K & Kaasa, S. (1992). Psychometric validation of the EORTC Core Quality of Life Questionnaire 30-item version and a diagnosis-specific module for head and neck cancer patients. Acta Oncologica. 31 (3) 311-321.Brady., M. J., Peterman. A Fitchett, G., Mo,M & Cella, D. (1999). A case for including spirituality in quality of life measurement in oncology. Psycho-Oncology. 8, 417-428.Brady., M J., Cella, D.F., Mo, F., Bonomi, A.E., Tulsky, D.S. Lloyd, S.R., Deasy, S., Cobleigh, M. & Shiomoto, G. (1997). Reliability and validity of the Functional Assessment of Cancer Therapy-Breast Quality of Life Instrument. J, of Clin Oncol. 15(3), 974-986.Brady, M.J., Peterman, A.H., Fitchett, G., Mo. M. & Cella.D. (1999). A Case for including spirituality in quality of life measurement in oncology. Psycho-Oncology, 8. 417-428Cassileth, B.R., Walsh, W.P. & Lusk, E.J. (1988). Psychosocial correlates of cancer survival: a subsequent report 3 to 8 years after cancer diagnosis. J. Clin. Oncol. 6. 1753-1759.Cella, D. (1990). Health promotion in oncology: a cancer wellness doctrine. J of Psychosoc. One 8, 17-31.Cella D.F. (1994). FACT Manual: Functional Assessment of Cancer Therapy Scales and the Functional Assessment of HIV Infection Scale. Rush-Presbyterian-St Luke;s Medical Center Chicago, Illinois.Cella, D.F. & Bonomi, A.E. (1996). The Functional Assessment of Caner Therapy and Functional assessment of HIV Infection quality of life measurement system (pp.203-214) In, B. Spilker(ED), Quality of Life and Pharmacoeconomics in Clinical Trials (2nd ed). Philadelphia: Lippencott-Raven.Chu C, Klein HE. Psychological and environmental variables in outcome of black schizophrenics. J Natl Med Assoc 1985; 77:793-796;
Cole, B. & Pargament, K. (1999). Re-creating your life: A spiritual/psychotherapeutic intervention for people diagnosed with cancer. Psycho-oncology, 8, 395-407.Costa, P.t. & McCrae, R.R. (1992a). Professional Manual: Revised NEO Personality Inventory and NEO Five-FActor Inventory. Odessa, Florida. Psychological Assessment Resources Inc.Costa P.T.& McCrae, R.R. (1992b). Normal personality assessment is clinical practice: The NEO Personality Inventory. Psychological Assessment. 4(1), 5-13.Cunningham, A.J. (1986). Information and Health in the many levels of man. Towards a more comprehensive theory of health and disease. Advances (J. Inst. Advancement of Health, Ny.) , 3 32-45.Cunningham, A.J. (1988). From neglect to support to coping: The evolution of psychosoicial intervention for cancer patients. In C.I., Cooper (ED) "stess and Breast Cancer." New York, John Wiley and Sons Ltd. 135-153.Cunningham, A.J. & Edmonds C.V.I. (1996). Group psychological therapy for cancer patiens: A point of view, and discussion of the hierarchy of options. Internat. J> Psychiat. in Med. 26(1), 51-82Cunningham, A.J. & Edmonds C.V.I. Jenkins, G.P. Pollack. H., Lockwood, G. A. Tritchier. D. and Warr. D. (1998). a randomized controlled trial of the effects of group psychological therapy on survival in women with metastatic breast cancer. Psycho-Oncology. 7. 508-517.Cunningham, A.J. Edmonds, C.V.I. & Williams, D. (1999). Delivering a very brief psychoeducational program to cancer patients and family members in a large group format. Psycho-Oncology 8, 177-182.Cunningham, A.J>, Lockwood, G.A. & Cunningham, J.A, (1991a). A relationship between perceived self-efficacy and quality of life in cancer patiens. Patient Education and counseling 17, 71-78.Cunningham, A.J.,Edmonds, C.V.I., Hampson, A.W., Hanson, H. Hovanec, M., Jenkins, G., & Tocco, E. K. (1991b). Helping cancer patients cope with, and combat, thier disease. Report on a group of psychoeducational program. Advances, 7, 41-56.Cunningham, A.J., Edmonds, C.V.I. , Jenkins. G. & Lockwood,G. (1995). A randomized comparison of two forms of a brief, group, psychoeducational program for cancer patients: Weekly sessions versus a "weekend intensive." Internat. J. Psychiat. in Med. 25, 173-189.Cunningham, A.J., Lockwood, G.A. & Edmonds, C.V.I. (1993). Which cancer patiens benefit most from a brief, group, coping skills program? Internat. J. Psychiat. in Med 23, 383-398.Cunningham, A.J., & Tocco, E.K. (1989). A randomized trial of group spychoeducational therapy for cancer patiens. Pat Ed & Counsel 14 101-114. Dancey, J., Zee, B., Osaba, D., Whitehead, M. Lu F., Kaizer L. et al. (1997). Quality of life scores: An independent prognostic variable in a general population of cancer patiens receiving chemotherapy. Quality of life Research 6 151-158.
Dattore, P.J., Shontz, F.C. & Coyne, L., (1980). Premorbid personality differentiation of cancer and non-cancer groups: A test of the hypotheses of cancer proneness. J. Consult Clin Psychol. 48. 388-394.Derogatis, L.R., Abeloff, M.D. & Melisaratos, N. (1979. Psychological coping mechanisms and survival time in a metastatic breast caner. J. Am Med. Assoc. 242 1504-1508. Edelman. S., Lemon, J., Bell, D.R. & Kidman, A.D. (1999). Effects of group CBT on the survival time of patiens with metastatic breast cancer. Psychol-Oncology 8 474-481.Edmonds, C.V. I. Lockwood, G.A. & Cunningham A. J. (1999). Psychological response to a long term group therpapy. A randomized trial metastatic breast cancer patients. Psycho-Oncology 8 74-91.Ell, K., Nishimoto, R., Morvay, T., Mantell, J. & Harnovitch, M. (1989). A longitudinal analysis of psychological adaptation among survivors of cancer. Cancer 63. 406-413.Fawzy, F.I. Fawzy.N.W., Hyun.C.S., Elashoff, R., Buthrie, D. Fahey, J.L. & Morton D.I., (1993). Malignant melanoma. Effects of an early structured psychiatric intervention, coping and affective state on recurrence and survival 6 years later. Arch Gen Psychiatry 50. 681-689.Fitchett, B., Cella, D. & Peterman, A. (1996). Spiritual beliefs and quality of life in cancer and HIV patients. Abstract presented at the Society for Scientific Study of Religion. November 1996.Fox.B.H. (1998). A hypotheses about Speigel et al's 1989 paper on psychosocial intervention and breast cancer survival. Psycho-Oncology 7 361-370.Funch, D.P. & Marshall. J. (1983). The Role of stress, social support and survival from breast cancer. J. Psychosom. Res. 27, 77-83.Garssen, b. & Goodkin, K. (1999). On the role of immunological factors as mediators between psychosocial factors and cancer progression. Psychiatry Research 85, 51-61.Goodkin, K.,, Antoni, M.H., & Blaney. P.H. (1986) Stress and hopelessness in the promotion of cervical intraepithelial neoplasia to invasive squamous cell carcinoma of the cervix. J. Psychosom Res 30 67-76.Gotay CC, Isaacs P, Pagano I. (2004). Quality of life in patients who survive a dire prognosis ompared to control cancer survivors. Psycho-Oncology 13: 882-892.
Gross, J.,(1989), Emotional expression in cancer onset and progression. Soc. Sci Med. 28. 1239-1248.Hahn, R.C. & Petini, D.B., (1988). Minnesota Multiphasic Personality Inventory-rated depression and the incidence of breast cancer. Cancer 61, 845-848.Hirshberg C, Barash MI. 1995. Remarkable Recovery: What Extraordinary Healings Tell Us About Getting Well and Staying Well. New York: The Berkeley Publishing Group.
Hislop, T.G., Waxler, N.E. Coldman, A.J., Elwood, J.S. & Kan, L., (1987). The prognostic significance of psychosocial factors in women with breast cancer. J.Chron. Dis. 40 729-735.Howard, K.I., Orlinksy, D.E. & Lueger, R.J. (1994). Clinically relevant outcome research in individual psychotherapy. British Journal of Psychiatry. 165-. 4-8.Huebscher, R.R. (1992a). Spontaneous remission of cancer. PhD. Thesis. U.M.I. Dissertation Services. Ann Arbor Michigan.Huebscher, R.R. (1992b). Spontaneous remission of cancer An example of health promotion. Nurse Practitioner Forum 3, 228-235.Ikemi, Y., Hakgawa, S., Nakagawa. S. et al. (1975). Psychosomatic consideration of cancer patients who have made a narrow escape for death. Dyn Psychiatric 8. 77-91.Ilnyckyj. A.,Farber, J., Cheang. M.D. & Weineman, B. H. (1994). A randomized controlled trial of psychotherapeutic intervention in cancer patients. Annals Royal College of Physicians & Surgeons of Canada. 27, 93-96.Irvine, D. & Sidani, S. (1997). A critical appraisal of the mental health and quality of life assessment tools: Utility for assessment and treatment planning for women with breast cancer. Health Canada.Jamison.R.N., Burish, T.G. & Wallston, K.A. (1987). Psychogenic factors in predicting survival of breast cancer patients. J. Clin. Oncol. 5 768-772.Jensen. M.R. (1987). Psychobiological factors predicting the course of breast cancer. J. Personality. 55 317-342.Jensen Hjermstad, M., Fossa,S.D., Bjordal, K & Kassa. S. (1995). Test/retest study of the European Organization for research and Treatment of Cancer Cove Quality of life Questionnaire. J of Clin Oncology 13(5) 1249-54.Katkin S, Zimmerman V, Rosenthal J, Ginsburg M. Using volunteer therapists to reduce hospital readmissions. Hosp Community Psychiatry 1975; 26:151-153.
Kemmler, G., Holzner, B., Kopp,M., Dunser, M., Margreter, R., Greil, R. et al. (1999). Comparison of two Quality of life instruments for cancer: The Functional Assessment of Cancer therapy-General and the European Organization for Research and Treatment of Cancer Quality of LIfe Questionnaire-C30. J of Clin. Oncology 17(9) 2932-2940. Kaasa, S., Mastekaasa, A. & Lund.E.(1989). Prognostic factors for patents with inoperable non-small-cell lung cancer, limited disease. Radiother .Oncol., 15 235-42.Kaplan, G.A. & REynolds. P. (1988). Depression and cancer mortality and morbidity: Prospective evidence from the Alameda County study. J. Behav. Med. 11. 1-13.Kaufman. E., & Micha, V. ( 1987). A model for psychotherapy with the good-prognosis cancer patient: conducted at a time when the patient is amenable to change. Pscyhosomatics 28, 540-548.Kennedy, B.J. Tellegen. A., Kennedy. S., & Havernick, N. (1976). Psychological response of patients cured of advanced cancer. Cancer. 38., 2184-2191.
Kreitler, S., Chaitchik, S. & Kreitler, H. (1993). Repressiveness: cause or result of cancer? Psycho-Oncolgoy. 2, 43-54LaBarba, R.C. (1970). Experiential and environmental factors in cancer. A review of research with animal. Psychosom Med. , 332 259-276.Larson DB, Milano MG. Making the case for spiritual interventions in clinical practice. J Mind/Body Medicine 1997; 2(1): 20-30.
Larson DB, Larson SS. 1994. The forgotten factor in physical and mental health: What does the research show? An independent study seminar published by the National Institute for Healthcare Research through a grant from the Templeton Foundation.
Linn, M. W., Linn, B.S., &Harris R. (1982). Effects of counseling for later stage cancer patients. Cancer 49. 1048-1055.Maunsell, E., Brisson.J. & Duschenes. L. (1995. Social support and survival among women with breast cancer. Cancer. 76(4) 631-637McDonald-Scott P. & Endicott, J. (1984). Informed versus blind. The reliability of cross-sectional ratings of psychopathology. Psychiatry Research. 12, 207-217.Meares A. (1980). What can the cancer patient expect from intensive medication? Australian Family Physician 9, 322-325.Meyer, R. J. & Mark, M. M. (1995). Effects of psychosocial interventions with adult cancer patients: A meta-analysis of randomized experiments. Health psychology. 14 101-108.Miller. T. (1991). The psychotherapeutic utility of the five-factor model of personality: A clinician's experience. Journal of Personality Assessment 57, 415-433.Miller WR, deBaca J. 1994. Quantum change: toward a psychology of transformation. In Heatherton T, Weinberger J, eds. Can Personality Change? Washington, DC: American Psychological Assocation, pp. 253-280.
Morganstern, H., Gellert, G.A. Walter. S.D., Ostefield, A.M. & Siegel, B.S. (1984). The impact of a psychosocial support program on survival with breast cancer: The importance of selection bias in a program evaluation.. Journal of Chronic Disease. 37(4). 273-282.Morris. T., Blake S. & Buckley. M (1985). Development of a method for rating cognitive responses to a diagnosis of cancer. Soc.Sci Med., 20(8) 795-802Morris, R., Pettingale, K.W. & Haybittle, J. L. (1992). Psychological response to cancer diagnoisis and disease outcome in patients with breast cancer and lymphoma. Psycho-Oncology. J. 105-114Mytko, J. J., & Knight, S. J. (1999). Body, mind and spirit: Towards the integration of religiousity and spirtuality in cancer quality of life research. Psycho-Oncology. 8. 439-450. Newton, B. W. (1982-83). The use of hypnosis in the treatment of cancer patients Am. J. Clin. Hypnosis. 25, 104-113.O’Regan B, Hirshberg C. (1993). Spontaneous Remission: An Annotated Bibliography. Sausalito, CA: Institute of Noetic Sciences.
Osaba, D., Aaronson, N., Zee, B., Sprangers, M & te Velde, A, (1997). Modification of the EORTC QLQ-C30 (version 2.0) based on content validity and reliability testing in large samples of patients with cancer. Quality of Life Research, 6 103-108.Osaba, D, Zee, B., Pater, J., Warr, D., Kaizer, L. & Latreille, J. (1994). Psychometric properties and responsiveness of the EORTC QLQ-30 in patients with breast, ovarian and lung cancer. Quality of Life Research. 3. 353-364.Oxman TE, Freeman DH, Manheimer ED. (1995). Lack of social participation or religious strength or comfort as risk factors for death after cardiac surgery in elderly. Psychosom Med 57:5-15.
Piedmont, R.I., (1998). The Revised NEO personality Inventory: Clinical and research applications: New York: Plenum Press.Pennington S. (1988). Healing yourself. McGraw, Toronto.Peteet, J.R. (1982). A closer look at the concept of support: some applications to the case of patiens with cancer. Gen. Hospital Psychiatry. 4 19-23.Pettingale, K.W., Morris, T., Greer, S. & Haybittle, J.L.(1985). Mental attitudes to cancer: An additional prognostic factor Lancet i. 750.Propst LR, Ostrom R, Watkins P, Dean T, Mashburn D. 1992. Comparative efficacy of religious and nonreligious cognitive-behavior therapy for the treatment of clinical depression in religious individuals. J Consult Clin Psychol 60:94-103.
Ramirez, A.J., Craig. T.K.J. Walson., J.P., Fentiman, I.S., North W.R.S. & Ruben's, R.D. (1989). Stress and relapse of breast cancer. British Med. J. 298. 291-293.Ratcliffe,M.A., Dawson. A.A., &Walker.L.G. (1995). Eysenck Personality Inventory L-Scores in patients with Dodgkin's disease and non-Hodgkins's lymphoma. Psycho-Oncology. 4 39-45.Rhodes, M.& Kreisteller,J.L., (2000). Reliability and validity of the FACT-G Spiritual Wellbeing scale in a community cancer population. Paper presented at the Society of Behavioral Medicine. April 6.Richardson, J. L., Shelton, D.R., Krailo. M. & Levine, A.M. (1900). The effects of compliance with treatment on survival among patients with hematologic malignancies. J of Clinical Oncology. 8(2) 356-364.Ringdal, G.I. & Ringdal, K. (1993). Testing the EORTC Quality of Life Questionnaire on cancer patients with heterogeneous diagnoses. Quality of Life Research 2. 9-140.Roberts AH. Contingency management methods in the treatment of chronic pain. In Bonica JJ, Lindblom U, Iggo A, eds. Advances in pain research and therapy. New York: Raven Press, 1983: 789;
Roberts AH, Kewman DG, Mercier L, Hovell M. The power of non-specific effects in healing: implications for psychosocial and biological treatments. Clin Psychol Rev 1993; 12: 375-391;
Roberts AH. The Powerful placebo revisited: magnitive of nonspecific effects. Mind/Body Medicine 1995; 1(1): 35-43.
Roud., P.C. (1986-87). Psychosocial variables associated with the exceptional survival of patients with advanced malignant disease. Int. J. Psychiatr. Med. 16. 113- 122.\Schatzman, L. ( 1991). Dimensional analysis: Notes on an alternative approach to the grounding of theory in qualitative research. In D.R. Maines (ED). " Social Organization and Social Process." (pp 303-314). NY., Aldine De Gruyter.Schipper. H. Goh, C.r. & Wang. T.L. (1995). shifting the cancer paradigm: Must we kill to cure? J Clin. Oncol. 13, 801-807.Seligman, M.E. (1995). the effectiveness of psychotherapy: The Consumer Reports study. Americana Psychologist 50 , 965-974Sharp., L.K., Knight, S.J,, Nadler, R,, Albers, M., Moran, E., Kuzel, T, et al (1999), Quality of life in low-income patients with metastatic prostate cancer: Divergent and convergent validity of three instruments. Quality of Life Research 8 461- Shekelle, R.B., Raynor, W. J. , ., Ostfeld, A.M. Garron, D.C. Bieliauskas, L.A., Liu, S.C. Maliza, C. & Ogelsby. P. (1981). Psychological depression and 17 year risk of death from cancer. Psychosom. Med. 43, 117-125.
Sklar, L.S, & Anisman, H. (1981. Stress and Cancer. Psychol. Bull. 89, 369-406.Somerfield, M. & Curbow, B. (1992). Methodological issues and research strategies in the study of coping with cancer. Soc. Sci. Med. 34(11), 1203-1216.Speigel,D. (1986). Psychological intervention with cancer patients. Psychocoical Oncology. 4 83-95.Spiegel, D, bloom, J.R, Kraemer, H.C. & Gottleib, E. (1989) Effect of psychosoical treatment on survival of patients with metastatic breast cancer. Lancet. Oct 14. 888-891.Spiegal, D. Bloom, J.R., and Yalom,I (1981). Group support for patients with metastatic cancer. Archives of General Psychiatry. 38. 527-533.Streiner, D. & Norman G (1989) . Health measurement scales: A practical guide to thier development and use. New York: Oxford University Press.Temoshok. L., Heller, B.W. Sagebiel, R.W., Blois, M.S., Sweet, D.M. Diclemente, R. J. and Gold., M. L. ((1985). The relationship of psychosoical factors to prognostic indications in cutaneous malignant melanoma. J. of Psychosomatic REs. 29 139-154.Temoshok, L., & Fawcett, J. (1987). Personality, coping style, emotion and cancer: Towards and integrative model. Cancer surveys. 6 545-567.Tulman, L. & fawcettl, J. (1996). Biobehavioral correlates of functional status following diagnosis of breast cancer. Report of a pilot study. Image Journal of Nursing Scholarship. 28. , 181Visintainer, M.A., Seligman, M.E.P. & Volpicelli, J. (1983). Helplessness, chronic stress and tumor development. Psychosom. Med. 45 75-76.Watson, M., Haviland, J. S., Greer, S,. Davidson,J, & Bliss, J. M. (1999) Influence of psychological response on survival in breast cancer: A populaton-based cohort study. Lancet 354Waxler-Morrison, N. , Hislop, T.G. , Meares, B. & Kan, L. (1991). Effects of social relationships on survival fo r women with breast cancer. A prospective treial. Social Science Medicine 33(2). 177-183.Weitzner, M.A, Meyers C.A. , Gelke, C.K., Byrne, K.S., Cella, D.F. & Levin, vV,A. (1995). The Functional Assessment of Cancer Therapy Scale. Development of a brain subscale and revalidation of the general version in patients with primary brain tumors. Cancer. 75(5) 1151-1161.Zonderman, A.B., Costa, P.T. & McCrae, R.R. (1989). Depression is a risk for cancer morbidity and mortality in a nationally representative sample. J. AM. Med Assoc. 262 1191-1195.


[*] The term aboriginal is used (instead of “Native American” or “American Indian”) since the author works in Canada where the term is used for the original inhabitants of a place (as it is similarly used in Australia, New Zealand, and other British Commonwealth countries). This term is preferred by the people themselves, as is also the term First Nations people. “Native North American” would be clumsy and would have a different meaning within the British Commonwealth as a person born in North America, and not necessarily a descendent of one of the original inhabitants of North America.
Post a comment
Write a comment:

Related Searches