Previously, studies suggest a causal link between diabetes and dementia. Paul K. Crane, from the University of Washington (Washington, USA), and colleagues analyzed data collected on 2,581 men and women, ages 65 and older between 1994 and 1996, enrolled in the Group Health Cooperative, who did not have dementia at the study’s start; an additional 811 subjects enrolled between 2000 and 2002. Participants were asked to return at 2-year intervals for dementia evaluation, and 2,067 of the participants, each of whom were members for at least 5 years prior to the study’s start and had at least five measurements of blood glucose or glycated hemoglobin (HbA1c) over 2 or more years prior to the study, had at least one follow-up visit. The final analysis encompassed 35,264 glucose measurements and 10,208 measurements of HbA1c obtained from 839 men and 1,228 women who had a baseline mean age of 76. The participants included 232 patients with diabetes. During a median follow-up of 6.8 years, 524 participants developed dementia, consisting of 74 with diabetes and 450 without. Patients without diabetes and who developed dementia had significantly higher average glucose levels in the 5 years before diagnosis of dementia), equating to a hazard ratio of 1.18. Among the patients with diabetes, glucose levels averaged 190 mg/dL in those who developed dementia versus 160 mg/dL in those who did not, equating tot a hazard ratio of 1.40. The study authors conclude that: “ Our results suggest that higher glucose levels may be a risk factor for dementia, even among persons without diabetes.”
Crane P.K., Walker R., Hubbard R.A., et al. “Glucose Levels and Risk of Dementia.” N Engl J Med 2013; 369:540-548.
Printed biocompatible components based on microelectromechanical systems (MEMS) technology pave the way towards smart prosthetics.
A diet rich in long-chain n-3 polyunsaturated fatty acids n-3 (PUFAs) may help to reduce the risk of rheumatoid arthritis, among women.
Consuming raw garlic may reduce lung cancer risk by as much as 44%.
Mitochondrial DNA levels, present in cerebral spinal fluid, emerges as a novel biomarker of Alzheimer’s Disease – at least a decade before symptoms manifest.
Molecular robots hone in on specific populations of human cells, directing therapeutic drugs to specific targets.
Sugar consumption fuels tumor growth, potentially explaining why people with Metabolic Syndrome are at risk for certain cancers.
Moderate exercise may help to alleviate tendinopathies, a range of diseases characterized by degeneration and chronic tendon pain.
Higher glucose levels are significantly associated with an increased risk of dementia, among older men and women without diabetes.
Exercise may improve cognitive function in those at-risk for Alzheimer’s Disease, by improving the efficiency of brain activity associated with memory.
Saliva from people who use cell phones as little as eight hours a month show increases in markers that correlate to potential cancer risk.
People who walk to work are 40% less likely to have diabetes, and 17% less likely to have high blood pressure, as compared to those who drive.
Sponge-like material, which expands and contracts in response to blood sugar levels, releases insulin contained in its core, as the body needs it.
As a form of commuting, bicycling has positive effects on weight, and parameters of cardiovascular health.
Consuming green tea may assist with blood sugar management
A cup of hot cocoa may help to control inflammation-related diseases such as diabetes, suggests an animal study.
Metal-oxide nanofiber based chemiresistive gas sensors offer greater usability for real-time breath tests on smart phones or tablet PCs in the near future.
When consumed with starchy foods, strawberries, bilberries, lingonberries, and chokeberries significantly reduce the postprandial insulin response, among women.
Generational shifts in metabolic risk factors suggest that today’s adults are less healthy than their predecessors.
Higher levels of mercury exposure – such as that which may occur from consumption of fish and shellfish – may increase the risks for type 2 diabetes.
The extent of a person’s energy expenditure is a key determinant in risk reductions for hypertension, hypercholesterolemia, diabetes, and coronary heart disease
Tip #192 - Stay Connected
Researchers from the University of Chicago (Illinois, USA) report that social isolation may be detrimental to both mental and physical health. The team analyzed data from the National Social Life, Health, and Aging Project, a nationwide US study involving 3,000 men and women, ages 57 to 85 years. They arrived at three key findings regarding the relationships between health and different types of isolation:
• The researchers found that the most socially connected older adults are three times as likely to report very good or excellent health compared to those who are least connected, regardless of whether they feel isolated.
• The team found that older adults who feel least isolated are five times as likely to report very good or excellent health as those who feel most isolated, regardless of their actual level of social connectedness.
• They determined that social disconnectedness is not related to mental health unless it brings feelings of loneliness and isolation.
Separately, Rush University Medical Center (Illinois, USA) researchers studied 906 older men and women, testing their motor functions (including grip, pinch strength, balance, and walking) and surveying their social activity, for a period of 5 years. Those study participants with less social activity were found to have a more rapid rate of motor function decline. Specifically, the team found that every one-point decrease in social activity corresponded to an increase in functional aging of 5 years, translating to a 40% higher risk of death and 65% higher risk of disability.