Health knowledge made personal
Join this community!
› Share page:
Go
Search posts:

Depression May Accelerate Cognitive Decline

Posted Sep 09 2013 10:07pm

In that major depression occurs in up to 20% of diabetics and it has been shown to increase the risk for retinopathy and other microvascular complications, as well as macrovascular complications like heart attack and stroke, researchers from the University of Seattle (Washington, USA) assessed whether depression raises the risks of  cognitive impairment, among type-2 diabetics.  Mark Sullivan and colleagues completed a 40-month cohort study of 2,977 subjects enrolled in the Action to Control Cardiovascular Risk in Diabetes-Memory in Diabetes (ACCORD-MIND) trial.  Depressed patients showed consistently greater declines in cognitive function on three separate assessment tests, even after adjustment for confounding factors  Observing that: “Depression in patients with type 2 diabetes was associated with greater cognitive decline in all domains, across all treatment arms, and in all participant subgroups assessed,” the study authors submit that: “Future randomized trials will be necessary to determine if depression treatment can lower the risk of cognitive decline in patients with diabetes.”

Sullivan MD, Katon WJ, Lovato LC, Miller ME, Murray AM, Horowitz KR, et al.  “Association of Depression With Accelerated Cognitive Decline Among Patients With Type 2 Diabetes in the ACCORD-MIND Trial.”  JAMA Psychiatry. 2013 Aug 14.

  
Celery – as well as artichokes and the herb Mexican oregano – contain apigenin and luteolin, flavonoid compounds that kill human pancreatic cancer cells.
Depression in patients with type 2 diabetes is a significant risk factor for dementia.
Drinking two cups of hot chocolate daily may help to offset declines in thinking and memory, among older adults.
Eating a low glycemic load diet that also follows the principles of the traditional Mediterranean diet may lower type-2 diabetes risk.
Printed biocompatible components based on microelectromechanical systems (MEMS) technology pave the way towards smart prosthetics.
A diet rich in long-chain n-3 polyunsaturated fatty acids n-3 (PUFAs) may help to reduce the risk of rheumatoid arthritis, among women.
Consuming raw garlic may reduce lung cancer risk by as much as 44%.
Mitochondrial DNA levels, present in cerebral spinal fluid, emerges as a novel biomarker of Alzheimer’s Disease – at least a decade before symptoms manifest.
Molecular robots hone in on specific populations of human cells, directing therapeutic drugs to specific targets.
Sugar consumption fuels tumor growth, potentially explaining why people with Metabolic Syndrome are at risk for certain cancers.
People taking selective antidepressants around the time of having surgery are found to have an increased risk of bleeding, transfusion, readmission, and death.
Yoga has positive effects on mild depression and sleep complaints, and improves symptoms associated with schizophrenia and ADHD.
Low levels of vitamin D associate with an increased risk of depression, in midlife.
Elevated levels of C-reactive protein, a marker of inflammatory disease, may associate with increased risk of psychological distress and depression.
Spouses of people who have a sudden heart attack are at increased risk of depression, anxiety, and suicide, even if their partner survives.
Psychological stress and depression can cause the loss of brain volume, thereby contributing to emotional and cognitive impairment.
Low levels of vitamin B-6 and B-12 are associated with an increased risk of impaired cognition.
People who survive a heart attack, but are depressed, face a difficult recovery prognosis.
Older women who get more exercise and watch less television time are less likely to be diagnosed with depression.
Self-determined motivation and perceived competence are important factors in persuading seniors to exercise more.
Anti-Aging Forum MLDP Join A4M
Tip #192 - Stay Connected
Researchers from the University of Chicago (Illinois, USA) report that social isolation may be detrimental to both mental and physical health. The team analyzed data from the National Social Life, Health, and Aging Project, a nationwide US study involving 3,000 men and women, ages 57 to 85 years. They arrived at three key findings regarding the relationships between health and different types of isolation:

• The researchers found that the most socially connected older adults are three times as likely to report very good or excellent health compared to those who are least connected, regardless of whether they feel isolated.

• The team found that older adults who feel least isolated are five times as likely to report very good or excellent health as those who feel most isolated, regardless of their actual level of social connectedness.

• They determined that social disconnectedness is not related to mental health unless it brings feelings of loneliness and isolation.

Separately, Rush University Medical Center (Illinois, USA) researchers studied 906 older men and women, testing their motor functions (including grip, pinch strength, balance, and walking) and surveying their social activity, for a period of 5 years. Those study participants with less social activity were found to have a more rapid rate of motor function decline. Specifically, the team found that every one-point decrease in social activity corresponded to an increase in functional aging of 5 years, translating to a 40% higher risk of death and 65% higher risk of disability.

» MORE
 
Post a comment
Write a comment: