Deficit In Body Fat From Early HIV Drugs Persists Years Later
Posted Jul 03 2010 8:52am
HIV-infected patients who lost subcutaneous fat as a result of taking first-generation antiretroviral drugs still had strikingly less body fat than non-infected controls five years after switching to newer medications, according to a study led by researchers at the San Francisco VA Medical Center and the University of California, San Francisco.
The deficit was particularly marked in leg and lower trunk fat, where body fat is associated with lower risk of cardiovascular disease, and less so in visceral and upper body fat, which is associated with increased cardiovascular risk.
The study appears in the July 17, 2010 issue of the journal AIDS.
HIV-infected patients who lost subcutaneous fat as a result of taking first-generation antiretroviral drugs still had strikingly less body fat than non-infected controls five years after switching to newer medications, according to a study led by researchers at the San Francisco VA Medical Center and the University of California, San Francisco.
The deficit was particularly marked in leg and lower trunk fat, where body fat is associated with lower risk of cardiovascular disease, and less so in visceral and upper body fat, which is associated with increased cardiovascular risk.
The study appears in the July 17, 2010 issue of the journal AIDS.