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Cranberry Juice Reduces Markers of Heart Disease

Posted Jul 19 2013 10:08pm

Characterized by central obesity, hypertension, and adverse glucose and insulin metabolism, Metabolic Syndrome is a condition associated with increased risk of type-2 diabetes and cardiovascular disease.  Previously, studies suggest that consumption of cranberries and cranberry  juice helps to reduce cardiovascular risk factors. T. Simao, from the Philadelphia University Center (UNIFIL) Londrina (Brazil), and colleagues enrolled 56 men and women with Metabolic Syndrome in a study in which subjects received either a folic-acid enriched cranberry juice, or control beverage, for 60 days.  Those participants who consumed the enriched juice showed an increase in adiponectin – a hormone with a key role in the regulation of insulin sensitivity and energy, as well as a decrease in homocysteine – a compound linked to an increased risk of cardiovascular disease.  As well, consumption of the enriched juice resulted in reduced measures of oxidative stress.  The study authors submit that: “In conclusion, the consumption of cranberry juice for 60 [days] was able to improve some cardiovascular risk factors.”

 Simao TN, Lozovoy MA, Simao AN, Oliveira SR, Venturini D, Morimoto HK, Miglioranza LH, Dichi I.  “Reduced-energy cranberry juice increases folic acid and adiponectin and reduces homocysteine and oxidative stress in patients with the metabolic syndrome.”  Br J Nutr. 2013 Jun 11:1-10.

  
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Estimated to affect 125 million people worldwide, psoriasis is a chronic inflammatory condition affecting the immune system that commonly manifests in the form of thick, red, scaly patches on the skin.

Researchers from Harvard Medical School (Massachusetts, USA) found that the risk of coronary disease is almost 30% greater in psoriasis patients, and stroke risk exceeded the rate of the general population by 12%. The risk did not vary by severity of psoriasis, as patients with moderate and severe disease had a similar prevalence of heart disease and stroke. Separately, a Copenhagen University (Denmark) team studied nearly 50,000 patients who had experienced their first heart attack between 2002 and 2006, following the 462 patients with psoriasis for an average of 19.5 months and the 48,935 controls for an average of 22 months. The team found that heart attack patients with psoriasis were 26% more likely to die from cardiovascular disease, or suffer from recurrent heart attacks or strokes, and were 18% more likely to die from all causes than those without the inflammatory skin disease.

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