Type-2 diabetes accounts for up to 95% of all diabetes cases in the world. Previous studies have suggested that people who drink four or more cups of coffee daily have a 50% lower risk of Type 2 diabetes. And every additional cup of coffee brings another decrease in risk of almost 7%. B. Cheng, from Tongji School of Pharmacy (China), and colleagues have identified two categories of compounds in coffee that significantly inhibit the misfolding of human islet amyloid polypeptide (hIAPP), posited to be a primary contributor to the onset of Type-2 diabetes. Specifically, caffeic acid and chlorogenic acid present in coffee were observed to exert protective effects on islet cells. The study authors conclude that: "the beneficial effects of coffee consumption on [Type-2 diabetes] may be partly due to the ability of the major coffee components and metabolites to inhibit the toxic aggregation of [human islet amyloid polypeptide].”
Cheng B, Liu X, Gong H, Huang L, Chen H, Zhang X, Li C, Yang M, Ma B, Jiao L, Zheng L, Huang K. “Coffee Components Inhibit Amyloid Formation of Human Islet Amyloid Polypeptide in Vitro: Possible Link between Coffee Consumption and Diabetes Mellitus.” J Agric Food Chem. 2011 Dec 28;59(24):13147-55.
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ANTI-AGING TIP OF THE DAY
Supercharge Your Cells
Telomeres are the endcaps on chromosomes, and telomeric shortening is thought to govern the number of times a cell can divide. Telomeres are also thought to be highly susceptible to damage by free radicals. Researchers from the US National Institute of Environmental Health Sciences (NIEHS; North Carolina, USA) studied multivitamin use and nutrient intakes, as well as telomere length, among 586 women, ages 35 to 74, enrolled in the Sister Study. Compared to non-multivitamin users, the team found that telomeres were 5.1% longer in those who took a daily multivitamin...
Type-2 diabetes accounts for up to 95% of all diabetes cases in the world. Previous studies have suggested that people who drink four or more cups of coffee daily have a 50% lower risk of Type 2 diabetes. And every additional cup of coffee brings another decrease in risk of almost 7%. B. Cheng, from Tongji School of Pharmacy (China), and colleagues have identified two categories of compounds in coffee that significantly inhibit the misfolding of human islet amyloid polypeptide (hIAPP), posited to be a primary contributor to the onset of Type-2 diabetes. Specifically, caffeic acid and chlorogenic acid present in coffee were observed to exert protective effects on islet cells. The study authors conclude that: "the beneficial effects of coffee consumption on [Type-2 diabetes] may be partly due to the ability of the major coffee components and metabolites to inhibit the toxic aggregation of [human islet amyloid polypeptide].”