Angiogenesis is a physiological process enabling the growth of new blood vessels from pre-existing ones. A vital mechanism for wound healing, angiogenesis is also a key process involved in tumor growth and progression. Several previous studies suggest that piperine, an alkaloid compound found abundantly in black pepper, has diverse physiological actions including the ability to kill cancer cells. Carolyn D. Doucette, from Dalhousie University (Canada), and colleagues explored the effect of piperine on angiogenesis, in a lab animal model. The team found that piperine inhibited the conversion of certain regulators of endothelial cell function and angiogenesis, as well as inhibited the pathway that is implicated in the proliferation and transition of tumors from a dormant state to a malignant one. The study authors conclude that: “these data support the further investigation of piperine as an angiogenesis inhibitor for use in cancer treatment.”
Doucette CD, Hilchie AL, Liwski R, Hoskin DW. “Piperine, a dietary phytochemical, inhibits angiogenesis.” J Nutr Biochem. 2012 Aug 16.
Probiotics help college-age students to reduce the duration of common colds.
Thanks to mechanization and computers, physical activity levels are dropping around the world due to changes in occupational activity.
Eight ounces of a low-calorie cranberry juice consumed daily modestly reduces hypertension (high blood pressure).
Suicide has overtaken traffic accidents as the leading cause of injury deaths in the United States.
A combination of sesame and rice brain oils lower blood pressure almost as well as prescription medication.
The World Heart Federation reports that half of people worldwide believe they should wait until age 30 before taking action to prevent disease and stroke.
Piperine, a compound found abundantly in black pepper, inhibits cellular mechanisms that are necessary in angiogenesis, a key process for tumor growth.
Interleukin-6 (IL-6), a chemical messenger in our immune system, may also trigger weight loss.
Moderate exercise may help people cope with anxiety and stress for an extended period of time post-workout.
University of North Carolina (US) team reports that a relatively small number of places in the human genome are associated with a large number of diseases.
Researchers created a membrane-bounded vesicle formed of peptides that may serve as a drug delivery system to safely treat cancer and neurodegenerative diseases
Consuming more cruciferous vegetables – such as brussels sprouts, broccoli, cauliflower, and bok choy – may slash a woman’s risk of breast cancer by 15%.
A class of drugs taken by approximately 20% of diabetics has been shown to significantly increase the risk of developing bladder cancer.
Nanoparticles, bound to compounds found in tea leaves, reduced tumors by 80%, in a lab animal model.
Researchers submit that by raising the Vitamin C recommended dietary allowance (RDA), cases of heart disease, stroke, and cancer might be slashed.
Physical activity – either mild or intense and before or after menopause – may reduce breast cancer risk, but substantial weight gain may negate these benefits.
Fetal exposure to the plastic additive BPA has been shown to alter mammary gland development and plays a role in the development of breast cancer in humans.
Carvacrol, a compound found in oregano, is shown to induce prostate cancer cell death.
Swedish researchers report that cadmium, present agricultural crops as a result of farm fertilizers, is linked to an increased incidence of breast cancers.
Whereas red meat may increase total, cardiovascular, and cancer death risks, appropriate substitutions may lower those same risks.
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54. Screenings Save Lives
Age-appropriate screening tests lead the list among all the things you can do to prevent yourself from getting sick. Screening tests can find diseases early when they are easier to treat. The age at which you will start having regularly scheduled screenings will vary, based on your sex, your age, your medical and family history, and other factors.
Men should have the following screenings:
• Cholesterol Checks: At least every 5 years, starting at age 35. If you smoke, have diabetes, or if heart disease runs in your family, start having your cholesterol checked at age 20.
• Blood Pressure: At least every 2 years