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Black Pepper Contains Anti-Cancer Compound

Posted Oct 18 2012 10:09pm

Angiogenesis is a physiological process enabling the growth of new blood vessels from pre-existing ones.  A vital mechanism for wound healing, angiogenesis is also a key process involved in tumor growth and progression.  Several previous studies suggest that piperine, an alkaloid compound found abundantly in black pepper, has diverse physiological actions including the ability to kill cancer cells.  Carolyn D. Doucette, from Dalhousie University (Canada), and colleagues explored the effect of piperine on angiogenesis, in a lab animal model. The team found that piperine inhibited the conversion of certain regulators of endothelial cell function and angiogenesis, as well as inhibited the pathway that is implicated in the proliferation and transition of tumors from a dormant state to a malignant one. The study authors conclude that: “these data support the further investigation of piperine as an angiogenesis inhibitor for use in cancer treatment.”

Doucette CD, Hilchie AL, Liwski R, Hoskin DW. “Piperine, a dietary phytochemical, inhibits angiogenesis.”  J Nutr Biochem. 2012 Aug 16.

  
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54. Screenings Save Lives
Age-appropriate screening tests lead the list among all the things you can do to prevent yourself from getting sick. Screening tests can find diseases early when they are easier to treat. The age at which you will start having regularly scheduled screenings will vary, based on your sex, your age, your medical and family history, and other factors.

Men should have the following screenings:
• Cholesterol Checks: At least every 5 years, starting at age 35. If you smoke, have diabetes, or if heart disease runs in your family, start having your cholesterol checked at age 20.
• Blood Pressure: At least every 2 years
 
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