Numerous epidemiological studies have reported the relationship between fruit intake and chronic diseases. Fruit intake provides the diet with nutrient and non-nutrient phytochemicals. Mangoes are a source of bioactive compounds with potential health-promoting activity: ascorbic and dehydroascorbic acids, carotenoids, phenolics compounds, fiber, terpenoids and others. Several studies have demonstrated the biological properties of compounds found in all parts of the mango plant, suggesting their beneficial effects on human health, particularly as antioxidant. It points out the need for studies to evaluate the impact of fruit intake on the modulation of risk factors of diseases. Furthermore, the utilization of agroindustry residues is one strategy for obtaining phytochemicals to be used as nutraceuticals or natural antioxidants.