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B Vitamins May Reduce Risk of Colorectal Cancer

Posted Jan 16 2013 10:07pm

Involving a total of 88,045 postmenopausal women who were recruited between 1993 and 1998; The Women's Health Initiative Observational Study covers the time period in which the United States introduced mandatory fortification of grain products with folic acid (a bioavailable form of folate).  Stefanie Zschabitz, from Fred Hutchinson Cancer Research Center (Washington, USA), and colleagues analyzed the diagnosis of 1,003 incident colorectal cancer cases in the study group that were ascertained as of 2009. The researchers observed that women with the highest average intakes of riboflavin (vitamin B2, over 3.97 mg per day) were at a 20% lower risk of colorectal cancer (as compared to women with the lowers average intakes at less than 1.8 mg).  Additionally, the highest intakes of pyridoxine (Vitamin B6, over 3.88 mg per day) were found to lower the risk by 20%  (as compared to women with the lowers average intakes at less than 1.52 mg).  The study authors conclude that: “Vitamin B-6 and riboflavin intakes from diet and supplements were associated with a decreased risk of [colorectal cancer] in postmenopausal women.”

Stefanie Zschabitz, Ting-Yuan David Cheng, Marian L Neuhouser, Yingye Zheng, Roberta M Ray, Joshua W Miller, et al.  “B vitamin intakes and incidence of colorectal cancer: results from the Women's Health Initiative Observational Study cohort.”  Am J Clin Nutr., December 19, 2012.

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#107 - Foil the Common Sleep Robbers
If you experience trouble falling asleep, or staying asleep, consider the following:

• An irregular or inconsistent schedule of being awake/asleep sets the biological stage for poor sleep. Set a regular schedule, particularly for the time at which you get up everyday.

• Avoid caffeine (commonly found in soda, soft drinks, coffee, and tea), which is a stimulant, for six hours before bedtime, longer if you know these substances give you trouble sleeping. Also avoid hidden sources of caffeine, such as chocolate and some over-the-counter pain and cold remedies.

• Avoid nicotine (from cigarettes or a skin patch), also a stimulant, for at least six hours prior to bedtime.

• Avoid alcohol after dinnertime. While a drink may help you fall asleep, it will probably cause you to awaken in the middle of the night.

• If you are on any prescription or over-the-counter medications, ask your doctor if any of them could be keeping you awake or causing you not to get a refreshing sleep.
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