Previous studies link a higher vitamin B status with a lower risk for cancer. To elucidate the exact mechanism by which this may occur, Keisuke Kuwahara, from the National Center for Global Health and Medicine (Japan), and colleagues studied 500 subjects (293 men and 207 women), ages 21 to 66 years, employed at two municipal offices in Japan. Observing that pyridoxal – one of three forms of vitamin B6 – associated with lower urinary 8-hydroxydeoxyguanosine (8-OHdG), a marker of oxidative DNA damage, in men, the study authors write that: “The results suggest that vitamin B6 plays a role against oxidative DNA damage.”
Keisuke Kuwahara, Akiko Nanri, Ngoc Minh Pham, Kayo Kurotani, et al. “Serum vitamin B6, folate, and homocysteine concentrations and oxidative DNA damage in Japanese men and women.” Nutrition, 24 June 2013.
Japanese team reports the successful generation of a successfully transplanted functional human liver using liver buds derived from pluripotent stem cells.
American Society of Nutrition reaffirms the health benefits of whole grain and bran foods, to reduce risks of diabetes, obesity, and heart disease.
British team identifies 22 metabolites linked to aging, one of which is correlated to birthweight.
Broken amyloid fibrils may be a cause of neurodegenerative diseases including Alzheimer’s.
Higher blood levels of Vitamin B6 associate with less damage to DNA, among men.
The prevalence of disability increases in the 2 years prior to death, with those who die at the oldest ages far more likely to have disability.
As a form of commuting, bicycling has positive effects on weight, and parameters of cardiovascular health.
People who believe stress adversely affects their health may be at increased risk of a cardiac event.
New telescopic contact lens may improve sight for macular degeneration patients.
Consuming green tea may assist with blood sugar management
Study results suggest that eating a combination of tomatoes and soy foods offers the most effective protection against prostate cancer.
Men who regularly suffer from sleep problems appear to have a significantly increased risk of developing prostate cancer.
Men who have Metabolic Syndrome may be at increased risk of diagnosis and death from prostate cancer.
Curcumin, the spice compound that gives curry its yellow color and pungent flavor, may inhibit formation of metastases, in a lab model of prostate cancer.
Eating red meat that has been cooked at high temperatures has been shown to significantly increase the risk of developing prostate cancer.
More than 6% of Americans ages 70 to 89 develop mild cognitive impairment (MCI) every year, and the condition appears to affect men more than women.
Study results suggest that men who take a daily vitamin E supplement may increase their risk of prostate cancer.
Married men with two or more children may be at significantly lower risk for having a fatal cardiovascular event
Being born and raised in a major urban area is associated with greater lifetime risk for anxiety and mood disorders.
Levels of nine specific proteins that decline with age can be reversed by testosterone treatment, suggesting beneficial effects for aging men.
Tip #192 - Stay Connected
Researchers from the University of Chicago (Illinois, USA) report that social isolation may be detrimental to both mental and physical health. The team analyzed data from the National Social Life, Health, and Aging Project, a nationwide US study involving 3,000 men and women, ages 57 to 85 years. They arrived at three key findings regarding the relationships between health and different types of isolation:
• The researchers found that the most socially connected older adults are three times as likely to report very good or excellent health compared to those who are least connected, regardless of whether they feel isolated.
• The team found that older adults who feel least isolated are five times as likely to report very good or excellent health as those who feel most isolated, regardless of their actual level of social connectedness.
• They determined that social disconnectedness is not related to mental health unless it brings feelings of loneliness and isolation.
Separately, Rush University Medical Center (Illinois, USA) researchers studied 906 older men and women, testing their motor functions (including grip, pinch strength, balance, and walking) and surveying their social activity, for a period of 5 years. Those study participants with less social activity were found to have a more rapid rate of motor function decline. Specifically, the team found that every one-point decrease in social activity corresponded to an increase in functional aging of 5 years, translating to a 40% higher risk of death and 65% higher risk of disability.