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Aspirin May Reduce Melanoma Risk

Posted Mar 29 2013 10:11pm

Previous studies have suggested that nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin, associate with decreased risk of gastric, colorectal, and breast cancers. Jean Tang, from Stanford University (California, USA), and colleagues studied the use of NSAIDs and melanoma – the deadliest form of skin cancer. The team assessed data collected from 59,806 postmenopausal Caucasian women, ages 50 to 79 years, enrolled in the Women's Health Initiative. The subjects were surveyed for their use of aspirin and nonaspirin NSAIDs and followed for a median period of 12 years to identify the development of melanomas. The researchers found that women who used aspirin were at 21% lower risk of melanoma, as compared to non-aspirin users. Further, each incremental increase in duration of aspirin use (less than one year of use, 1 to 4 years of use, and five or more years of use) correlated with an 11% lower risk of melanoma. Thus, women who used aspirin for five or more years were at 30% lower melanoma risk, as compared to women who did not take aspirin.  Submitting that "aspirin works by reducing inflammation," the study authors conclude that: " Postmenopausal women who used [aspirin] had a significantly lower risk of melanoma, and longer duration of [aspirin] use was associated with greater protection.”

Gamba, Christina A., Swetter, Susan M., Stefanick, Marcia L. Kubo, Jessica Desai, Tang, Jean Y, et al.  “Aspirin is associated with lower melanoma risk among postmenopausal Caucasian women.”  Cancer, 11 March 2013.

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Anti-Aging Forum MLDP Join A4M
Tip #141 - Men – Get Moving
Previous studies have suggested that physical activity decreases the risk of certain cancers. University of California, Los Angeles (USA) researchers have found that men who work in jobs that require a continuous level of high physical effort are at reduced risks of developing prostate cancer. The team compared the physical activity of 392 workers who developed prostate cancer with 1,805 men similarly employed and of similar age. Amongst a group of aerospace workers, 64% of whom were involved in work that required sustained and high levels of physical activity, the odds for prostate cancer were 45% lower, as compared to their less active counterparts.

Don’t underestimate the health benefits of physical activity, be it leisure-time exercise, competitive sports, or at-work exertion. Check with your anti-aging physician to make sure the level of your physical activity is appropriate for your medical needs.
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