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A case of thymic carcinoma complicating scleroderma on which radiotherapy was remarkably effective

Posted Mar 12 2011 1:31am
The case in a 57-year-old male was diagnosed as a thymic carcinoma in the Masaoka stage II based on results of imaging and histological findings. The surgical perfect resection of the carcinoma was judged to be difficult, and radiotherapy was chosen for making the irradiation of 6000cgy to the tumor. In chest CT images after the irradiation, obvious reduction in the tumor was observed, and in Ga scintigraphic images, disappearance of the hot spot was confirmed. According to the reduction in the mediastinum tumor, swelling/hardening of fingers had been disappeared and the remarkable improvement in the subjective symptoms of scleroderma had been obtained. It was suspected that some autoimmunity mechanisms possibly concern the onset of scleroderma and thymic carcinoma, as a matter of great interest.


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