Dr. Chris P.'s Posts

Conference: “New Insights into Healthspan and Diseases of Aging: From Molecular to Functional... by Dr. Chris P. Doctor of Philosophy

Posted in: Blog Posts in Aging & Senior Health There’s a Keystone Symposium on this subject Jan 31-Feb 5 2010:Aging can be defined as the gradual loss of the ability of the organism to maintain homeostasis. Our aim w ... Read on »

Sí se puede by Dr. Chris P. Doctor of Philosophy

Posted in: Blog Posts in Aging & Senior Health Just to follow up on that last post asking you to help the SENS Foundation win $5000 — it worked! SENS came in first, and won the grand prize. The margins were pretty na ... Read on »

Help raise $5000 for SENS – by leaving an online comment by Dr. Chris P. Doctor of Philosophy

Posted in: Blog Posts in Aging & Senior Health The SENS Foundation (which organizes the Strategies for Engineered Negligible Senescence conferences ) is in the running for the $5000 grand prize in 3banana’s Share to ... Read on »

RIP for MFRTA? by Dr. Chris P. Doctor of Philosophy

Posted in: Blog Posts in Aging & Senior Health A prominent scholar of the CLK-1 story has called the coroner on the mitochondrial free radical theory of aging ( MFRTA ). From Lapointe & Hekimi:When a theory of agin ... Read on »

Sunday Funnies by Dr. Chris P. Doctor of Philosophy

Posted in: Blog Posts in Aging & Senior Health (From the Perry Bible Fellowship. For the previous installment of Sunday Funnies, see here.) Read on »

Conference: Singularity Summit, October 3-4, New York by Dr. Chris P. Doctor of Philosophy

Posted in: Blog Posts in Aging & Senior Health I attended the inaugural Singularity Summit back in 2006 — it was full of ideas, certainly, but I came away mostly skeptical and disillusioned about the quality of think ... Read on »

SENS4, Session 21: Tissue engineering by Dr. Chris P. Doctor of Philosophy

Posted in: Blog Posts in Aging & Senior Health Gabor Forgacs gave a very interesting talk about using bioprinting to build entire organs from scratch. He argued that while traditional scaffold-based methods of tissue engin ... Read on »

SENS4, Session 18: Recent advances in cell therapies by Dr. Chris P. Doctor of Philosophy

Posted in: Blog Posts in Aging & Senior Health Daniel Kraft spoke about stem cell transplantation in bone marrow. They developed an alternative method of ‘making room’ in bone marrow for new stem cells that us ... Read on »

SENS4, Session 16: Delivering genes, proteins and larger structures in vivo by Dr. Chris P. Doctor of Philosophy

Posted in: Blog Posts in Aging & Senior Health Carlos Barbas talked about altering the activity of individual genes using zinc finger recombinases. They have developed an automated approach for producing enzymes that can a ... Read on »

SENS4, Session 15: Rejuvenating the immune system by Dr. Chris P. Doctor of Philosophy

Posted in: Blog Posts in Aging & Senior Health Justin Rebo spoke about some initial experiments that show it’s feasible to selectively remove anergic T cells from old mice. The basic idea: remove some blood from a mo ... Read on »

SENS4, Sessions 18 and 21 by Dr. Chris P. Doctor of Philosophy

Posted in: Blog Posts in Aging & Senior Health Selected talks from Sessions 18 and 21:Daniel Kraft spoke about stem cell transplantation in bone marrow. They developed an alternative method of ‘making room’ in ... Read on »

SENS4, Sessions 15 and 16 by Dr. Chris P. Doctor of Philosophy

Posted in: Blog Posts in Aging & Senior Health A couple of talks from Sessions 15 & 16:Justin Rebo spoke about some initial experiments that show it’s feasible to selectively remove anergic T cells from old m ... Read on »

SENS4, Session 12: Novel anti-cancer approaches by Dr. Chris P. Doctor of Philosophy

Posted in: Blog Posts in Aging & Senior Health Paul Hallenbeck of Neotropix spoke about a promising new treatment for neuroendocrine cancers. Initial trials of the “Seneca Valley Virus” were conducted on patien ... Read on »

SENS4, Sessions 9 and 10: Rejuvenating extracellular material by Dr. Chris P. Doctor of Philosophy

Posted in: Blog Posts in Aging & Senior Health A couple of interesting talks from Sessions 9 and 10:Mark Pepys talked about treating amyloidosis by targeting serum amyloid P component (SAP), which is present in all amyloid ... Read on »

SENS4, Session 6: Eliminating recalcitrant intracellular molecules: other by Dr. Chris P. Doctor of Philosophy

Posted in: Blog Posts in Aging & Senior Health Claude Wischik spoke about preventing aggregation of tau protein, which is implicated in Alzheimer’s disease. Clinical trials of their aggregation-inhibiting drug Rember ... Read on »

SENS4, Session 5: Eliminating recalcitrant intracellular molecules: the lysosome by Dr. Chris P. Doctor of Philosophy

Posted in: Blog Posts in Aging & Senior Health Jeffrey Grubb spoke about new methods for delivering missing enzymes to the lysozomes of patients suffering from lysosomal storage diseases. Several of these should be able to ... Read on »

SENS4, Session 4: Adult regenerative capacity by Dr. Chris P. Doctor of Philosophy

Posted in: Blog Posts in Aging & Senior Health Brandon Reines presented a counterintuitive result on regeneration: sometimes old animals have a higher regenerative capacity than young animals. In particular, if you punch a ... Read on »

SENS4 coverage by Dr. Chris P. Doctor of Philosophy

Posted in: Blog Posts in Aging & Senior Health Our contributor Kristen Fortney is at the fourth Strategies for Engineered Negligible Senescence ( SENS4 ) meeting in Cambridge, England. Over the next few days, she’ll ... Read on »

Back from the dead by Dr. Chris P. Doctor of Philosophy

Posted in: Blog Posts in Aging & Senior Health Ouroboros has been slumbering for the past couple of months — this was for a variety of reasons, mostly to do with the editor’s other professional obligations. Apo ... Read on »

Lecture: Gregory Verdine, “Chemical biology of aging and cancer” by Dr. Chris P. Doctor of Philosophy

Posted in: Blog Posts in Aging & Senior Health I’m sitting in the Drexler Auditorium of the Buck Institute, where I’ve been working over the last six months. Today we’re being treated to an off-schedule & ... Read on »

Dr. Chris P.

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