Liver diseases especially the ones associated with obstruction of bile
Bone diseases, healing fractures and rickets
Leukaemia
Hyperparathyroidism
Chronic alcoholism
Many drugs affect the level of blood level of alkaline phosphatase including antibiotics, hormones, analgesics, steroids, methyldopa, propranolol, allopurinol, tricyclic antidepressants, chlorpromazine, oral contraceptives, tranquillisers and oral anti-diabetics.
Less-than-normal levels may be seen in:
Poor nutrition, deficiency of proteins, vitamin C or magnesium
Less-than-normal levels may be seen in: