Many UC sufferers often post questions about whether or not to pursue immuno-suppressive drug treatments such as remicade or 6mp. Unfortunately not everyone weighs the long term risks. I knew undergoing several of those treatments myself that there were various risks. I had little success with any of them. However I believe that the treatments I did undertake were sufficient to have side effects. I knew that remicade affects the pancreas in a small percentage of patients so I was not surprised when my surgeon told me and my family after the first surgery that my pancreas was a little harder than it should be and is something I would need to keep an eye on going forward.