Insulin resistance is a major feature of Type 2 diabetes. now, an international group of researchers has discovered a gene that seems to promote insulin resistance in bodily tissues (fat, liver and muscle).
Unlike most of the genes that have been shown to cause diabetes, the new gene, called Insulin Receptor Substrate 1 (IRS1), doesn't affect how insulin is created in the pancreas, but rather, how the body responds to insulin already in the bloodstream, say the researchers, whose work will be published in Nature Genetics Sept. 6.
The research was conducted by teams from the UK, Canada, France and Denmark. Genetic material was drawn from more than 6000 French subjects