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Gene Therapy for Periodontal Gum Disease--Improving Quality of Life & Health!

Posted Mar 08 2009 3:36pm

   Researchers at the University of Michigan have successfully shown that genetic therapy can be used to defray the development of gum disease.  Using gene transfer to treat life threatening conditions is not new, but the U-M group is the first known to use the gene delivery approach to show potential in treating chronic conditions such as periodontal disease.  "This is so important because the next wave of improving medical therapeutics goes beyond saving life, and moves forward to improving the quality of life,” said researcher Dr. Giannobile. 
    The pre-clinical study was done in collaboration with Targeted Genetics.   Human trial results that showed the same gene therapy approach used to stop periodontal disease had positive affects in patients with rheumatoid arthritis, another chronic disabling condition. The company tested 127 human subjects and showed a 30 percent improvement in pain relief, and gain of function, among other enhancements using the gene treatment.

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