Healthy people are not susceptible to stenotrophomonas maltophilia. As is the case in any situation involving the hospitalization of a patient with CF, the necessary contact precautions should be used to prevent the spread of Stenotrophomonas maltophilia. Strict adherence to proper cross-infection protocol has been very effective in reducing the risk of transferring a stenotrophomonas infection between patients in a hospital setting.
Fortunately, sten. malt. is far less likely to cause infection than PA. "Several studies in the US and elsewhere have been performed to find out the effect of Steno colonization on lung function and morbidity in CF patients, and none of them found that Steno actually causes a significant effect, unlike B. cepacia, for example. It just seems to like to sit in the cf lung." (M B Avison, PhD. University of Bristol, UK. www.bris.ac.uk/bcare/BGG)
It has a very limited ability to cause infection in humans and is only potentially lethal when it infects the bloodstream causing bacteremia. Overall, infections of sten. malt. are quite rare. They can be treated using a synergistic approach of intravenous medications that are targeted to gram-negative bacteria. This may involve treatment with colymycin and tobramycin used together.