Myth #1: Only Caucasians have the cystic fibrosis gene.
Posted Aug 03 2008 9:05pm
Fact: Although Caucasians and people of European descent are the ones most likely to have the CF gene, people of any ethnicity can have it. The statistics below show CF mutations* broken down by race and ethnicity.
Caucasian
Odds that both parents are carriers: 1 in 625
Chance of having a child with CF:1 in 2500
Mutation detection by screening: 90%
Hispanic American
Odds that both parents are carriers: 1 in 2,100
Chance of having a child with CF:1 in 8,500
Mutation detection by screening: 57%
African American
Odds that both parents are carriers: 1 in 4,200
Chance of having a child with CF:1 in 17,000
Mutation detection by screening: 69%
Asian American
Odds that both parents are carriers: 1 in 8,100
Chance of having a child with CF:1 in 32,400
Mutation detection by screening: unknown
* the most commonly known 25 mutations
These statistics and probabilities will be very different for mixed race couples. This data is based on Genetic Medicine 4(5):379-91. 2002.
Caucasian
Odds that both parents are carriers: 1 in 625
Chance of having a child with CF: 1 in 2500
Mutation detection by screening: 90%
Hispanic American
Odds that both parents are carriers: 1 in 2,100
Chance of having a child with CF: 1 in 8,500
Mutation detection by screening: 57%
African American
Odds that both parents are carriers: 1 in 4,200
Chance of having a child with CF: 1 in 17,000
Mutation detection by screening: 69%
Asian American
Odds that both parents are carriers: 1 in 8,100
Chance of having a child with CF: 1 in 32,400
Mutation detection by screening: unknown
* the most commonly known 25 mutations
These statistics and probabilities will be very different for mixed race couples. This data is based on Genetic Medicine 4(5):379-91. 2002.