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Systemic Inflammation in Chronic Obstructive Pulmonary Disease and Asthma: Relation with Comorbidities

Posted Dec 25 2009 10:05pm


Physical inactivity and metabolic syndrome are relevant conditions leading to systemic inflammation in the general population. Recent data indicate that physical inactivity and coexisting metabolic syndrome are also independently related to systemic inflammation in patients with COPD. Concerning asthma, only limited data about systemic inflammatory markers exist. Some studies found systemic inflammatory markers to be elevated in patients with nonallergic asthma and obese patients with asthma. Further research should elucidate the complex relationship between obstructive lung disease, coexisting conditions, systemic inflammation accompanying these different conditions, and the causative role of systemic inflammation for comorbidities in COPD and asthma.

Read the complete article from The Proceedings of the American Thoracic Society- click here

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