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Increasing oxygen flow has risks and benefits for COPD patients on LTOT

Posted Feb 23 2010 9:17am

By Mark Cowen

Increasing the nocturnal oxygen flow in hypercapnic chronic obstructive pulmonary disease (COPD) patients undergoing long-term oxygen therapy (LTOT) improves nocturnal oxygenation, but may also result in increased hypercapnia and respiratory acidosis in the morning, research suggests.

“Several COPD treatment guidelines recommend increasing oxygen flow during sleep to avoid nocturnal desaturation,” explain Daniel Samolski, (Hosand gas exchange effects,” they add.pital de la Santa Creu i Sant Pau, Barcelona, Spain) and team.

“However, such an increase could have deleterious clinical and gas exchange effects,” they add.

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