Chronic cough and sputum production predict COPD exacerbation
Posted Apr 23 2009 5:25pm
By Philip Ford
Chronic production of cough and sputum are closely linked to exacerbations of chronic obstructive pulmonary disease (COPD), say researchers who recommend specific therapeutic interventions to reduce the use of healthcare resources in patients with the disease.
Pierre-Régis Burgel (Hôpital Cochin, Paris, France) and co-workers explain that, “although studies suggest that chronic cough and sputum production are important manifestations in COPD subjects, available data are mostly based on epidemiologic studies.”
Because such studies do not allow for precise patient phenotyping, “the clinical features associated with chronic cough and sputum production in COPD subjects remain to be established,” the investigators say.
To better understand the features associated with chronic cough and sputum production in individuals with COPD, Burgel and team analyzed cross-sectional data from 433 COPD patients, 321 of whom had chronic cough and sputum production.
Writing in the journal Chest, the authors report that all patients were similar in terms of age, FEV1, body mass index, and presence of comorbidities.