Here is some very interesting research information on the effects of stem cell stimulation by StemTech's StemEnhance product. More info at the link above. StemEnhance® has a primary purpose of releasing adult stem cells and secondary benefit of increasing the natural production of PEA in the brain. However it's main ingredient, a concentrate of "AFA" is known as natures "super food" because it contains the full spectrum of Vitamins, Minerals and other nutritional ingredients as detailed below. Aphanizomenon flos-aquae (AFA) Nutrition profile:
AFA contains more chlorophyll than any other natural food, 3 to 5 times more than even wheat grass! Chlorophyll detoxifies the body from internally generated poisons and the waste products of general metabolism. Chlorophyll also protects us from external environmental pollutants we come in contact with each day.
Chlorophyll is a very important part of the AFA. Its molecular structure is almost the same as that of the hemoglobin, which is responsible for carrying oxygenated blood throughout the body. AFA is the prime nutrient, and chlorophyll is the central molecule for increasing the oxygen availability to your system. Chlorophyll is vital for the body's rapid assimilation of amino acids. AFA is the highest known source of chlorophyll. Chlorophyll Content per 10 grams:
Much attention in recent years has been given to the antigenotoxicity of chlorophyll. Chlorophyll, however, is known to be converted into pheophytin, pyropheophytin, and pheophorbide in processed vegetable food and following ingestion by humans. Studies were conducted on the antimutagenic and tumoricidal potencies of these compounds. All the chlorophyll derivatives tested exhibit identical antimutagenic effect towards 3-methylcholanthrene (3-MC), suggesting that the porphyrin nucleus may complex directly with the mutagen. It does not exclude, however, another mechanism of activity involving inactivation the enzymatic transformation of 3-MC. In contrast, the action of N'-nitro-N'-nitrosoguanidine (MNNG) depends upon structural differences between the chlorophyll derivatives. It is significantly lower when the phytol-containing pheophytin and pyropheophytin are tested as to that of the phytol-lacking pheophorbide. The higher concentrations of the chlorophyll derivatives were required to reduce the mutagenicity of MNNG than needed for 3-MC. The cytotoxicity of chlorophyll derivatives against tumor cells also was evaluated. The cellular uptake and inhibition of myeloma cell multiplicity were found to be greater for pheophorbide than for pheophytin. Calculated on the amount of cell associated chlorophyll derivative, however, pheophytin was more cytostatic/cytotoxic than pheophorbide. The results presented in this report indicate that food sources that yield chlorophyll derivatives may play a significant role in cancer prevention.
AFA is an abundant source of phycocyanin, the blue pigment found in the AFA. Similar to chlorophyll, phycocyanin protects the body against various toxic substances found in our food, air and water. Recent research has revealed that phycocyanin is an effective antioxidant and promotes healthy joint functioning.
Study of Phycocyanin
Antioxidant and anti-inflammatory properties of C-phycocyanin from AFA
Romay C, Armesto J, Remirez D, Gonzalez R, Ledon N, Garcia I Pharmacology Department, National Center for Scientific Research, CNIC, Havana, Cuba. Objective: Phycocyanin is a pigment found in blue-green algae which contains open chain tetrapyrroles with possible scavenging properties. We have studied its antioxidant properties.
Materials and Methods: Phycocyanin was evaluated as a putative antioxidant in vitro by using: a) luminol-enhanced chemiluminescence (LCL) generated by three different radical species (O2-, OH., RO.) and by zymosan activated human polymorphonuclear leukocytes (PMNLs), b) deoxyribose assay and c) inhibition of liver microsomal lipid peroxidation induced by Feascorbic acid. The antioxidant activity was also assayed in vivo in glucose oxidase (GO)-induced inflammation in mouse paw.
Results: The results indicated that phycocyanin is able to scavenge OH. (IC50 = 0.91 mg/mL) and RO. (IC50 = 76 microg/mL) radicals, with activity equivalent to 0.125 mg/mL of dimethyl sulphoxide (DMSO) and 0.038 microg/mL of trolox, specific scavengers of those radicals respectively. In the deoxyribose assay the second-order rate constant was 3.56 x 10(11) M(-1) S(-1), similar to that obtained for some non-steroidal anti-inflammatory drugs. Phycocyanin also inhibits liver microsomal lipid peroxidation (IC50 = 12 mg/mL), the CL response of PMNLs (p < 0.05) as well as the edema index in GO-induced inflammation in mouse paw (p < 0.05).
Conclusions: To our knowledge this is the first report of the antioxidant and anti-inflammatory properties of c-phycocyanin. Inflamm Res 1998 Jan;47(1):36-41