Resveratrol Shows Anti-Inflammatory Benefit in Human Study
Resveratrol is a compound found in certain plants and foods, including grape skins and red wine. Recent studies have tied resveratrol to longer life, enhanced athletic performance, reduced risk of colorectal and prostate cancer, and reduced inflammation. Many of these potential benefits are tied to resveratrol's antioxidant capacity.
While these antioxidant effects have been demonstrated in animal models and in in vitro (in "test tube") models, they have not all been shown in an in vivo ("in an organism") human model. In fact, we believe this to be the first study of resveratrol's antioxidant and anti-inflammation mechanism in humans.
In this new NIH-funded (National Institutes of Health) study, researchers from the State University of New York at Buffalo randomly gave healthy, normal-weight participants either a placebo or 40mg of resveratrol daily for 6 weeks. The researchers took fasting blood samples prior to the start of the study and at weeks 1, 3, and 6. The researchers analyzed reactive oxygen species (ROS), a common group of oxidizing compounds found in the body along with other measures of oxidation, and multiple measures of inflammation.