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Mad cow disease detected on Madrid farm Friday, January 9, 2009

Posted Apr 09 2009 7:13pm
Mad cow disease detected on Madrid farm

By: thinkSPAIN , Friday, January 9, 2009

The regional Environment ministry for Madrid has issued a statement to inform that a ten-year-old cow from a farm in Galapagar diagnosed with Bovine Spongiform Encephalopathy (BSE) on December 29th, has been put down at a local slaughterhouse.

There have been six confirmed cases of the disease since 2000 in the Madrid region, the previous last being in 2004.

Last year, ten thousand inspections were carried out in the region, where there are around 4,800 cattle farms.

The ministry assures that measures are already in place that ensure that this last case does not constitute any kind of risk to the food chain.

http://www.thinkspain.com/news-spain/16102/mad-cow-disease-detected-on-madrid-fa

RESUMEN EPIDEMIOLÓGICO SOBRE LAS ENCEFALOPATÍAS ESPONGIFORMES TRANSMISIBLES EN ESPAÑA AÑO 2008 (ENERO- NOVIEMBRE)

Número de CASOS EEB detectados en España por año de detección

Año 2000 2 Año 2001 83 Año 2002 134 Año 2003 173 Año 2004 138 Año 2005 103 Año 2006 68 Año 2007 40 Año 2008 21 Total acumulado 762

http://www.eeb.es/pags/resumen_EET_2008.pdf

DATOS FOCOS PRURITO LUMBAR 2008 1) RESUMEN EVOLUCIÓN TEMBLADERA (AÑOS 2000 A NOV 2008)

http://www.eeb.es/pags/informe_scrapie_08.pdf

Eurosurveillance, Volume 13, Issue 15, 10 April 2008 Rapid communications Two cases of variant Creutzfeldt-Jakob disease reported in Spain in 2007 and 2008 J de Pedro Cuesta ()1 Instituto de Salud Carlos III, Department of Applied Epidemiology, National Centre of Epidemiology, Madrid, Spain

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Citation style for this article: de Pedro Cuesta J. Two cases of variant Creutzfeldt-Jakob disease reported in Spain in 2007 and 2008. Euro Surveill. 2008;13(15):pii=18831. Available online: http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=18831

Date of submission: 09 April 2008

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In 2005, the first case of variant Creutzfeldt-Jakob disease (vCJD) was reported in Spain, in a woman born in 1978 with clinical onset of symptoms in 2004 [1]. She subsequently died in 2005.

Recently, two more laboratory-confirmed vCJD cases were reported to the Spanish CJD state registry. In February 2006, a woman born in 1957 developed progressive cognitive deterioration, and died in December 2007 with suspected sporadic CJD (typical EEG in October 2007) MM at codon 129 and no mutations in PRPN gene. A man born in 1967 had onset in May 2007 with psychiatric symptoms, and after several months developed progressive cognitive decline with dementia, typical MRI, MM at codon 129, no mutations in PRPN gene. He died in February 2008. Post-mortem, neuropathology with histochemistry confirmed vCJD in both cases. No clear specific dietary habits, blood donations or reception were recorded. Neither case appears to have visited the United Kingdom before 2004.

The latest two cases were resident in the same region of the country, Castilla y Leon, but no link between them was established.

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References

Centro Nacional de Epidemiología, Instituto de Salud Carlos III. First case of vCJD reported in Spain. Euro Surveill. 2005;10(8):E050804.1. Available from: http://www.eurosurveillance.org/ew/2005/050804.asp#1

http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=18831

Monday, September 01, 2008

Two cases of variant Creutzfeldt-Jakob disease reported in Spain in 2007 and 2008

http://creutzfeldt-jakob-disease.blogspot.com/2008/09/two-cases-of-variant-creut

see rise in sporadic CJD cases in Spain ;

http://www.eurocjd.ed.ac.uk/sporadic.htm

Sunday, March 16, 2008 MAD COW DISEASE terminology UK c-BSE (typical), atypical BSE H or L, and or Italian L-BASE March 16, 2008

http://bse-atypical.blogspot.com/2008/03/mad-cow-disease-terminology-uk-c-bse.ht

Sunday, August 10, 2008

Thursday, July 10, 2008 A Novel Human Disease with Abnormal Prion Protein Sensitive to Protease update July 10, 2008

http://cjdmadcowbaseoct2007.blogspot.com/2008/07/novel-human-disease-with-abnorm

Thursday, July 10, 2008 A New Prionopathy update July 10, 2008

http://cjdmadcowbaseoct2007.blogspot.com/2008/07/new-prionopathy-update-july-10-

MY COMMENTS, for whatever they are worth ;

A New Prionopathy OR more of the same old BSe and sporadic CJD

http://creutzfeldt-jakob-disease.blogspot.com/2008/08/new-prionopathy-or-more-of

Communicated by: Terry S. Singeltary Sr.

[In submitting these data, Terry S. Singeltary Sr. draws attention to the steady increase in the "type unknown" category, which, according to their definition, comprises cases in which vCJD could be excluded. The total of 26 cases for the current year (2007) is disturbing, possibly symptomatic of the circulation of novel agents. Characterization of these agents should be given a high priority. - Mod.CP]

http://pro-med.blogspot.com/2007/11/proahedr-prion-disease-update-2007-07.html

http://www.promedmail.org/pls/askus/f?p=2400:1001:6833194127530602005::NO::F2400

There is a growing number of human CJD cases, and they were presented last week in San Francisco by Luigi Gambatti(?) from his CJD surveillance collection.

He estimates that it may be up to 14 or 15 persons which display selectively SPRPSC and practically no detected RPRPSC proteins.

http://www.fda.gov/ohrms/dockets/ac/06/transcripts/1006-4240t1.htm

http://www.fda.gov/ohrms/dockets/ac/06/transcripts/2006-4240t1.pdf

JOURNAL OF NEUROLOGY

MARCH 26, 2003

RE-Monitoring the occurrence of emerging forms of Creutzfeldt-Jakob

disease in the United States

Email Terry S. Singeltary:

flounder@wt.net

I lost my mother to hvCJD (Heidenhain Variant CJD). I would like to comment on the CDC's attempts to monitor the occurrence of emerging forms of CJD. Asante, Collinge et al [1] have reported that BSE transmission to the 129-methionine genotype can lead to an alternate phenotype that is indistinguishable from type 2 PrPSc, the commonest sporadic CJD. However, CJD and all human TSEs are not reportable nationally. CJD and all human TSEs must be made reportable in every state and internationally. I hope that the CDC does not continue to expect us to still believe that the 85%+ of all CJD cases which are sporadic are all spontaneous, without route/source. We have many TSEs in the USA in both animal and man. CWD in deer/elk is spreading rapidly and CWD does transmit to mink, ferret, cattle, and squirrel monkey by intracerebral inoculation. With the known incubation periods in other TSEs, oral transmission studies of CWD may take much longer. Every victim/family of CJD/TSEs should be asked about route and source of this agent. To prolong this will only spread the agent and needlessly expose others. In light of the findings of Asante and Collinge et al, there should be drastic measures to safeguard the medical and surgical arena from sporadic CJDs and all human TSEs. I only ponder how many sporadic CJDs in the USA are type 2 PrPSc?

http://www.neurology.org/cgi/eletters/60/2/176#535

THE PATHOLOGICAL PROTEIN

Hardcover, 304 pages plus photos and illustrations. ISBN 0-387-95508-9

June 2003

BY Philip Yam

CHAPTER 14 LAYING ODDS

Answering critics like Terry Singeltary, who feels that the U.S. under- counts CJD, Schonberger conceded that the current surveillance system has errors but stated that most of the errors will be confined to the older population.

http://www.thepathologicalprotein.com/

Diagnosis and Reporting of Creutzfeldt-Jakob Disease Singeltary, Sr et al. JAMA.2001; 285: 733-734. Vol. 285 No. 6, February 14, 2001 JAMA

Diagnosis and Reporting of Creutzfeldt-Jakob Disease

To the Editor: In their Research Letter, Dr Gibbons and colleagues1 reported that the annual US death rate due to Creutzfeldt-Jakob disease (CJD) has been stable since 1985. These estimates, however, are based only on reported cases, and do not include misdiagnosed or preclinical cases. It seems to me that misdiagnosis alone would drastically change these figures. An unknown number of persons with a diagnosis of Alzheimer disease in fact may have CJD, although only a small number of these patients receive the postmortem examination necessary to make this diagnosis. Furthermore, only a few states have made CJD reportable. Human and animal transmissible spongiform encephalopathies should be reportable nationwide and internationally.

Terry S. Singeltary, Sr Bacliff, Tex

1. Gibbons RV, Holman RC, Belay ED, Schonberger LB. Creutzfeldt-Jakob disease in the United States: 1979-1998. JAMA. 2000;284:2322-2323. FREE FULL TEXT

http://jama.ama-assn.org/cgi/content/extract/285/6/733?maxtoshow=&HITS=10&hits=1

http://jama.ama-assn.org/cgi/content/full/285/6/733?maxtoshow=&HITS=10&hits=10&R

2 January 2000 British Medical Journal U.S. Scientist should be concerned with a CJD epidemic in the U.S., as well

http://www.bmj.com/cgi/eletters/320/7226/8/b#6117

15 November 1999 British Medical Journal vCJD in the USA * BSE in U.S.

http://www.bmj.com/cgi/eletters/319/7220/1312/b#5406

Creutzfeldt Jakob Disease

http://creutzfeldt-jakob-disease.blogspot.com/

http://creutzfeldt-jakob-disease.blogspot.com/2008/01/cjd-hgh-body-snatchers.htm

http://creutzfeldt-jakob-disease.blogspot.com/2008/01/risk-factors-for-sporadic-

http://creutzfeldt-jakob-disease.blogspot.com/2008/01/creutzfeldt-jakob-disease-

http://creutzfeldt-jakob-disease.blogspot.com/2007/12/risk-assessment-of-transmi

http://creutzfeldt-jakob-disease.blogspot.com/2007/12/risk-factors-for-sporadic-

http://creutzfeldt-jakob-disease.blogspot.com/2006/11/on-question-of-sporadic-or

USA PRION UNIT BLOG

http://prionunitusaupdate2008.blogspot.com/

Sunday, April 20, 2008 Progress Report from the National Prion Disease Pathology Surveillance Center April 3, 2008

Atypical forms of BSE have emerged which, although rare, appear to be more virulent than the classical BSE that causes vCJD.

see full text ;

http://prionunitusaupdate2008.blogspot.com/2008/04/progress-report-from-national

CJD TEXAS (cjd clusters)

http://cjdtexas.blogspot.com/

USA WRITTEN CJD QUESTIONNAIRE ???

http://cjdquestionnaire.blogspot.com/

The statistical incidence of CJD cases in the United States has been revised to reflect that there is one case per 9000 in adults age 55 and older. Eighty-five percent of the cases are sporadic, meaning there is no known cause at present.

http://www.cjdfoundation.org/fact.html

Tuesday, August 19, 2008

Atypical BSE (BASE) Transmitted from Asymptomatic Aging Cattle to a Primate

http://bse-atypical.blogspot.com/2008/08/atypical-bse-base-transmitted-from.html

Sunday, December 28, 2008

MAD COW DISEASE USA DECEMBER 28, 2008 an 8 year review of a failed and flawed policy

Greetings,

I thought a quick review of the Bush's terribly flawed and failed mad cow disease policy, from the illegal feeding of literally millions and millions of pounds of highly suspect, and banned mad feed, to the failed BSE surveillance program, all of which exposed, needlessly, millions of people to the mad cow agent i.e. Transmissible Spongiform Encephalopathy. ...

Parentage-based DNA traceback in beef and dairy cattle 2008

http://www.ars.usda.gov/sp2UserFiles/Place/54380570/HeatonPublications/HeatonPar

48 hour traceback for BSE mad cow disease in the USA ???

NOT in your lifetime !

8 YEARS IN REVIEW OF THE MAD COW DEBACLE IN THE USA ;

FOR IMMEDIATE RELEASE Statement May 4, 2004 Media Inquiries: 301-827-6242 Consumer Inquiries: 888-INFO-FDA

Statement on Texas Cow With Central Nervous System Symptoms

snip...full text ;

http://bse-atypical.blogspot.com/2008/12/mad-cow-disease-usa-december-28-2008-8.



Terry S. Singeltary Sr.
P.O. Box 42
Bacliff, Texas USA 77518
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