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CREUTZFELDT JAKOB TSE PR ...

Posted Dec 25 2012 5:14pm
CREUTZFELDT JAKOB TSE PRION DISEASE HUMANS END OF YEAR REVIEW DECEMBER 25, 2012
ICD-9 046.1; ICD-10 A81.0


Prion Disease Cases in Texas by Year (2002-2011)



2002200320042005200620072008200920102011
Sporadic CJD (sCJD)
confirmed47795913111612
probable1558324685
possible1310111200
Variant CJD (vCJD) 0000100000
Familial CJD (fCJD)1001111220
Iatrogenic CJD (iCJD) 0000000000
Sporadic fatal insomnia(sFI)0000010002
Fatal familial insomnia(FFI) 0000000020
Total715131811141921219


Creutzfeldt-Jakob Disease Sporadic and Familial Case Count





Creutzfeldt-Jakob Disease Surveillance Data for Reporting Years 2002-2011
A total of 165 people died from CJD during 2002-2011. Texas has had one variant CJD case in 2006.
Investigators have concluded that the patient was a former resident of the United Kingdom
where exposure was likely to have occurred.






CJD 2002-2011


*Case numbers per year

Texas CJD Cases by Age and Gender 2002-2011



2002200320042005200620072008200920102011Total
Age
< 55
3
3
2
2
3
3
4
1
7
4
32
≥ 55
4
12
11
16
8
11
15
20
21
15
133
Gender
Male
3
6
10
10
9
5
10
9
12
11
85
Female
4
9
3
8
2
9
9
12
16
8
80



CJD Cases by County 2000-2010


CJD county map(1)










Last updated August 24, 2012





PLEASE NOTICE THE TWO OUTBREAKS NO ONE SPEAKS OF IN TEXAS, explained away by geographical boundaries and mathematics there from, which we all know is a hoax. CJD clusters can happen close to borders, yet, explained away with population total, even though the cluster was geographically centered. TSE prion disease know no boundaries or borders, and TSE prion disease know no age groups. ...TSS


Merry Christmas everyone. ...warmest regards, terry










Wednesday, November 9, 2011



sporadic FFI or nvCJD in TEXAS ?








Case report Sporadic fatal insomnia in a young woman: A diagnostic challenge: Case Report TEXAS


HOW TO TURN A POTENTIAL MAD COW VICTIM IN THE USA, INTO A HAPPENSTANCE OF BAD LUCK, A SPONTANEOUS MUTATION FROM NOTHING.


OR WAS IT $$$















USA PRION UNIT LATEST HUMAN TSE PRION DISEASE UPDATE AUGUST 14, 2012



National Prion Disease Pathology Surveillance Center Cases Examined1 (August 14, 2012)



1996 & earlier 28 cases of sporadic CJD.


see steady increase to ;


2010 cases of sporadic CJD 216.


2011 cases of sporadic CJD 214.



snip...



1 Listed based on the year of death or, if not available, on year of referral;


2 Cases with suspected prion disease for which brain tissue and/or blood (in familial cases) were submitted;


3 Disease acquired in the United Kingdom;


4 Disease was acquired in the United Kingdom in one case and in Saudi Arabia in the other case;


5 Includes 8 cases in which the diagnosis is pending, and 18 inconclusive cases;


6 Includes 10 (9 from 2012) cases with type determination pending in which the diagnosis of vCJD has been excluded.


The Sporadic cases include 16 cases of sporadic Fatal Insomnia (sFI) and 42 cases of Variably Protease-Sensitive Prionopathy (VPSPr) and 2224 cases of sporadic Creutzfeldt-Jakob disease (sCJD).



snip...see full case reports here ;







Tuesday, December 18, 2012


Bioassay Studies Support the Potential for Iatrogenic Transmission of Variant Creutzfeldt Jakob Disease through Dental Procedures







Sunday, December 9, 2012


Prions, prionoids and pathogenic proteins in Alzheimer disease







Tuesday, December 04, 2012


Veterans health administration information systems as a resource for rare disorders research: Creutzfeldt-Jakob disease as a paradigm








Friday, November 23, 2012


sporadic Creutzfeldt-Jakob Disease update As at 5th November 2012 UK, USA, AND CANADA



snip...



Greetings BSE-L members et al, and others,


Confucius is confused again on the infamous ‘classification pending sporadic creutzfeldt jakob disease’ cpsCJD, (because nvCJD has been ruled out).


Confucius is confused about why the increase of these cpsCJD cases in the USA and Canada which we have been seeing, but I saw no reports in the UK surveillance reports of the infamous North American Classification Pending Sporadic Creutzfeldt Jakob disease cases.


if truly a supposedly sporadic spontaneous disease, would you not see these cpsCJD cases popping up all over the world in random ??


or, could these cpsCJD cases be of a North American zoonotic or iatrogenic from North American zoonoses sub-clinical source ??


or both ??


with so many documented Transmissible Spongiform Encephalopathy TSE prion disease in so many different species here in North America, and consumption there from, I believe that this should be at the forefront of research. ... Confused Confucius...flounder




USA


*** 5 Includes 8 cases in which the diagnosis is pending, and 18 inconclusive cases;


*** 6 Includes 10 (9 from 2012) cases with type determination pending in which the diagnosis of vCJD has been excluded.


Canada


*** 3. Final classification of 48 cases from 2009, 2010, 2011 and 2012 is pending.


MEXICO


clueless


AS OF AUGUST 2012 ;


CJD UPDATE USA


1 Listed based on the year of death or, if not available, on year of referral;


2 Cases with suspected prion disease for which brain tissue and/or blood (in familial cases) were submitted;


3 Disease acquired in the United Kingdom;


4 Disease was acquired in the United Kingdom in one case and in Saudi Arabia in the other case;


*** 5 Includes 8 cases in which the diagnosis is pending, and 18 inconclusive cases;


*** 6 Includes 10 (9 from 2012) cases with type determination pending in which the diagnosis of vCJD has been excluded.


*** The Sporadic cases include 16 cases of sporadic Fatal Insomnia (sFI) and 42 cases of Variably Protease-Sensitive Prionopathy (VPSPr) and 2224 cases of sporadic Creutzfeldt-Jakob disease (sCJD).








CJD Deaths Reported by CJDSS1, 1994-20122


As of Oct 31, 2012


Deaths of Definite and Probable CJD


Year Sporadic Iatrogenic Familial GSS FFI vCJD Total


1994 2 0 0 1 0 0 3


1995 3 0 0 0 0 0 3


1996 13 0 0 0 0 0 13


1997 16 0 1 1 0 0 18


1998 22 1 0 1 0 0 24


1999 27 2 2 1 0 0 32


2000 32 0 0 3 0 0 35


2001 27 0 2 1 0 0 30


2002 31 0 2 2 0 1 36


2003 27 1 1 0 0 0 29


2004 42 0 1 1 0 0 44


2005 41 0 1 1 0 0 43


2006 39 0 1 3 1 0 44


2007 35 0 0 4 0 0 39


2008 48 0 1 0 0 0 49


2009 48 0 3 2 0 0 53


2010 35 0 3 0 0 0 38


2011 41 0 2 1 0 1 45


2012 20 0 0 0 0 0 20


Total 549 4 20 22 1 2 598


1. CJDSS began in 1998


2. Data before 1998 are retrospective and partial, data from 1998 to 2008 are complete, and data for 2009 - 2012 are provisional


3. Final classification of 48 cases from 2009, 2010, 2011 and 2012 is pending.








snip...see full text ;









Tuesday, November 6, 2012


Transmission of New Bovine Prion to Mice, Atypical Scrapie, BSE, and Sporadic CJD, November-December 2012 update







Saturday, March 5, 2011


MAD COW ATYPICAL CJD PRION TSE CASES WITH CLASSIFICATIONS PENDING ON THE RISE IN NORTH AMERICA








Tuesday, June 1, 2010



USA cases of dpCJD rising with 24 cases so far in 2010










Monday, April 5, 2010


UPDATE - CJD TEXAS 38 YEAR OLD FEMALE WORKED SLAUGHTERING CATTLE EXPOSED TO BRAIN AND SPINAL CORD MATTER








Monday, March 29, 2010


Irma Linda Andablo CJD Victim, she died at 38 years old on February 6, 2010 in Mesquite Texas








CJD TEXAS 38 YEAR OLD FEMALE WORKED SLAUGHTERING CATTLE EXPOSED TO BRAIN AND SPINAL CORD MATTER








Thursday, May 27, 2010


CDC - INQUIRY ABOUT vCJD DEATH OF SLAUGHTER HOUSE WORKER IRMA LINDA ANDABLO








Archive Number 20100405.1091 Published Date 05-APR-2010


Subject PRO/AH/EDR> Prion disease update 1010 (04)


snip...


[Terry S. Singeltary Sr. has added the following comment:



"According to the World Health Organisation, the future public health threat of vCJD in the UK and Europe and potentially the rest of the world is of concern and currently unquantifiable. However, the possibility of a significant and geographically diverse vCJD epidemic occurring over the next few decades cannot be dismissed.










Friday, October 23, 2009



2000-2008 Creutzfeldt-Jakob 23 Data Disease for Friday October Reporting Surveillance Texas Years










Sunday December 16 2007



Creutzfeldt-Jakob Disease Surveillance in Texas 2000-2006









2011 Monday, September 26, 2011



L-BSE BASE prion and atypical sporadic CJD









Wednesday, March 28, 2012



VARIABLY PROTEASE-SENSITVE PRIONOPATHY IS TRANSMISSIBLE, price of prion poker goes up again $










*** The discovery of previously unrecognized prion diseases in both humans and animals (i.e., Nor98 in small ruminants) demonstrates that the range of prion diseases might be wider than expected and raises crucial questions about the epidemiology and strain properties of these new forms. We are investigating this latter issue by molecular and biological comparison of VPSPr, GSS and Nor98.






Tuesday, June 26, 2012




Creutzfeldt Jakob Disease Human TSE report update North America, Canada, Mexico, and USDA PRION UNIT as of May 18, 2012




type determination pending Creutzfeldt Jakob Disease (tdpCJD), is on the rise in Canada and the USA










Monday, July 23, 2012



The National Prion Disease Pathology Surveillance Center July 2012









Monday, August 06, 2012



Atypical neuropathological sCJD-MM phenotype with abundant white matter Kuru-type plaques sparing the cerebellar cortex










Saturday, October 6, 2012



TRANSMISSION, DIFFERENTIATION, AND PATHOBIOLOGY OF TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES 2011 Annual Report










Tuesday, November 6, 2012



Transmission of New Bovine Prion to Mice, Atypical Scrapie, BSE, and Sporadic CJD, November-December 2012 update










National Prion Disease Pathology Surveillance Center


Cases Examined1


(August 14, 2012)









see full text ;



Tuesday, November 6, 2012


Transmission of New Bovine Prion to Mice, Atypical Scrapie, BSE, and Sporadic CJD, November-December 2012 update








older cjd reports here ;










Monday, February 13, 2012


Creutzfeldt Jakob Disease Report update USA and TEXAS Sunday, February 12, 2012


National Prion Disease Pathology Surveillance Center Cases Examined1 (August 19, 2011) including Texas









Sunday, December 2, 2012


CANADA 19 cases of mad cow disease SCENARIO 4: ‘WE HAD OUR CHANCE AND WE BLEW IT’








Friday, December 14, 2012


Susceptibility Chronic Wasting Disease (CWD) in wild cervids to Humans 2005 - December 14, 2012









Wednesday, February 16, 2011


IN CONFIDENCE


SCRAPIE TRANSMISSION TO CHIMPANZEES


IN CONFIDENCE







why do we not want to do TSE transmission studies on chimpanzees $



snip...


5. A positive result from a chimpanzee challenged severly would likely create alarm in some circles even if the result could not be interpreted for man. I have a view that all these agents could be transmitted provided a large enough dose by appropriate routes was given and the animals kept long enough. Until the mechanisms of the species barrier are more clearly understood it might be best to retain that hypothesis.


snip...


R. BRADLEY








Friday, February 11, 2011


Atypical/Nor98 Scrapie Infectivity in Sheep Peripheral Tissues








Monday, April 25, 2011


Experimental Oral Transmission of Atypical Scrapie to Sheep


Volume 17, Number 5-May 2011








Sunday, April 18, 2010


SCRAPIE AND ATYPICAL SCRAPIE TRANSMISSION STUDIES A REVIEW 2010








Thursday, December 20, 2012


OIE GROUP RECOMMENDS THAT SCRAPE PRION DISEASE BE DELISTED AND SAME OLD BSe WITH BOVINE MAD COW DISEASE







Monday, August 20, 2012



CASE REPORTS CREUTZFELDT-JAKOB DISEASE: AN UNDER-RECOGNIZED CAUSE OF DEMENTIA













see the Duke, Pa, Yale, and Mexican study here, showing the misdiagnosis of CJD TSE prion disease as Alzheimers ;













Wednesday, May 16, 2012



Alzheimer’s disease and Transmissible Spongiform Encephalopathy prion disease, Iatrogenic, what if ?



Proposal ID: 29403



















































































RIP MOM 12/14/97 confirmed hvCJD...TSS December 25, 2012



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