Prevalence of xenotropic murine leukaemia virus-related virus in patients with chronic fatigue syndrome in the Netherlands: retr
Posted Feb 26 2010 3:01pm
Published 25 February 2010, doi:10.1136/bmj.c1018 Cite this as: BMJ 2010;340:c1018
Frank J M van Kuppeveld, associate professor experimental virology1,5,6, Arjan S de Jong, molecular medical microbiologist1,5, Kjerstin H Lanke, research technician1,5,6, Gerald W Verhaegh, senior research fellow2,6, Willem J G Melchers, molecular medical microbiologist1,5,6, Caroline M A Swanink, medical microbiologist1, Gijs Bleijenberg, professor psychology4,5,7, Mihai G Netea, professor experimental internal medicine3,5, Jochem M D Galama, professor clinical virology1,5, Jos W M van der Meer, professor internal medicine3,5 1 Department of Medical Microbiology, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, Netherlands , 2 Department of Urology, Radboud University Nijmegen Medical Centre, 3 Department of Internal Medicine, Radboud University Nijmegen Medical Centre, 4 Expert Centre for Chronic Fatigue, Radboud University Nijmegen Medical Centre, 5 Nijmegen Institute for Infection, Inflammation, and Immunity, Nijmegen, 6 Nijmegen Centre for Molecular Life Sciences, Nijmegen, 7 Nijmegen Centre for Evidence Based Practice, Nijmegen
Objective The presence of the retrovirus xenotropic murine leukaemiavirus-related virus (XMRV) has been reported in peripheral bloodmononuclear cells of patients with chronic fatigue syndrome.Considering the potentially great medical and social relevanceof such a discovery, we investigated whether this finding couldbe confirmed in an independent European cohort of patients withchronic fatigue syndrome.... read more .