During the first day of increasing the dose I was very ill. I was shaking, sleepy, confused and could hardly move due to extreme weakness . I normally feel weak but the medication worsened it and almost made me feel as if I were in the early days of my illness again.
After the first day I began to feel a little better. I could move about as before - which is slowly, but that is normal for me - and my speech improved to the same level it was before taking the medicine.
Although I felt no real improvement in terms of the majority of symptoms associated with ME/CFS I have to say that my sleep has improved. I can now sleep at night and have been awake during the day for the full week. This is a big improvement for me, as I struggle with sleep; usually staying awake for days and never awakening during the daylight hours. So, we will see.
I am going to increase the dose tomorrow, as requested by the doctor. My daily dose of Pregabalin will then be 450 mg. I will update you as to my progress.