Low-dose naltrexone is the only treatment that has helped me significantly in the 8 yeard I;ve had CFS!  Not everyone with CFS can tolerate it, though - you should start with a very low dose and work up.

I don't know anything about fatty livers, but your doctor should be able to tell you whether it would be safe.  Anyone on LDN gets routine blood tests for liver function anyway.

The best source for information on LDN is:

 http://www.lowdosenaltrexone.org/

Good luck!

Sue Jackson

www.livewithcfs.blogspot.com