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Alzheimer's and Dementia News 251

Posted Apr 20 2013 12:00pm
The wife of Willy Mays dies from complications caused by Alzheimer's Disease, and a recap of ongoing clinical trials around the world

By +Bob DeMarco
+Alzheimer's Reading Room  


Alzheimers Dementia
Wife of Willie Mays Dies of Alzheimer's Disease

The wife of baseball legend Willie Mays has died. The Giants announced the death of Mae Louise Allen Mays late Friday, saying she had died in her sleep at the couple's home after a long battle with Alzheimer's Disease. She was 74 years old.

A Study of Brain Aging in Vietnam War Veterans

Traumatic brain injury (TBI) and post traumatic stress disorder (PTSD) are common combat related problems and may be associated with a greater risk of Alzheimer's disease (AD). The purpose of this study is to examine the possible connections between TBI and PTSD, and the signs and symptoms of AD on Veterans as they age. Follow the link if you know a veteran that is interested in enrolling in this study.

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Curcumin and Yoga Therapy for Those at Risk for Alzheimer's Disease

While this clinical trial is not yet recruiting it will be. You might want to examine the inclusion criteria and then book mark the page to apply when it is open to new participants.

A Clinical Trial of Exendin-4 for the Treatment of Alzheimer's Disease

Exendin-4 (or Exenatide) is a medication currently used to treat diabetes, but it has shown promising results in tests of its effectiveness in protecting neurons from damaging processes associated with Alzheimer's disease. It is possible that Exendin-4 may be a suitable treatment for Alzheimer's disease, which involves the gradual deterioration and death of neurons. Researchers are interested in comparing the effects of Exendin-4 with placebo to determine long-term treatment outcomes for individuals with early-stage Alzheimer's disease or mild cognitive impairment. This study is currently recruiting new participants.
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Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation

The purpose of this study is to assess the safety, tolerability and biomarker efficacy of Gantenerumab and Solanezumab in individuals who have an autosomal dominant Alzheimer's disease (ADAD) mutation. This study is currently recruiting new participants.

Intervention Study to Improve Life and Care for People With Dementia and Their Caregivers in Primary Care (Germany)

The purpose of this study is to test the efficacy of implementing a subsidiary support system for persons with dementia living at home. This subsidiary support system is initiated by a Dementia Care Manager (DCM), a nurse with dementia-specific advanced training. The main goals are to improve quality of life and health care of the person with dementia and reduce caregiver´s burden. Not yet recruiting, bookmark and follow if interested.

Multidisciplinary Intervention for Challenging Behaviour (Agitation) in Patients With Dementia (Norway)

The increasing prevalence of dementia is a major challenge to the health authorities in most countries. Nearly all the persons suffering from dementia experience behavioural and psychological symptoms (BPSD). The prevalence of BPSD is particularly high in nursing homes. BPSD are often treated with psychotropic drugs even though the evidence for effect is minimal and the risk of serious adverse events is considerable. All the major treatment recommendations advise that non-pharmacological measures should be applied first when treating BPSD even though the evidence for such treatment is limited. The investigators will conduct a pilot study of a non-pharmacological treatment for BPSD. The method has been developed in Norway and has already been implemented in a number of nursing homes in the county of Nordland. The study is currently recruiting new participants.

Study of Factors Influencing Post-stroke Dementia (France)

If the risk of dementia occurrence after stroke is well known, few data exist about the factors influencing positively or negatively the developement of cognitive disorders or dementia. The aim of the study is so to determine prospectively the clinical, biological, lesional and pharmacological factors associated with post-stroke dementia by the long-term follow-up of a stroke patient cohort. The study is currently recruiting new participants.

The Primary Care - Dementia Assessment and Treatment Algorithm (Canada)

Alzheimer's disease (AD) and related forms of dementia currently affect over 400,000 individuals in Canada and the numbers of community dwelling older adults with AD is rapidly growing. AD is associated with over $15 billion annually in care costs. Most individuals with AD are under the care of primary care providers (PCPs) including family physicians and primary care nurses. The evaluation and management of AD is challenging for PCPs and the quality of care provided to older adults with AD by PCP could be improved which would optimize outcomes for this vulnerable population. Provision of quality care to older adults with AD involves implementation of best practices as outlined in guidelines such as the Canadian Consensus Conference Guidelines on the Diagnosis and Treatment of Dementia. Utilizing a group of dementia researchers, PCPs, other knowledge users, and individuals affected by AD, this project will develop practical, clinically relevant resources for primary care physicians and nurses to aid in the evaluation of older adults with AD. The study is currently recruiting new participants.

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