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What disease can cause lytic bone lesions, bone marrow replacement, polycythemia, thrombocytopenia, hepatosplenomegaly and chron

Posted by Larz

40 y/o hispanic male. HCT: 49 at first visit, trending up to 55. platelets at 250k on first visit, trending down to 50. Lytic lesions in L spine, ribs, skull.  Diffuse marrow replacement on MRI, including areas that bone appears normal on CT.  Differntial white count all normal, IGM, IGG levels normal.  SPEP and epo level is pending.  No enhancing masses on CT.  Lytic lesions do enhance on MRI. 


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prostatic carcinoma
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