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Resveratrol trial in multiple myeloma suspended…

Posted May 08 2010 12:00am

I read the news about the SRT501 (a special high-dose formulation of resveratrol; for general info on resveratrol, see:  http://en.wikipedia.org/wiki/Resveratrol ) clinical trial suspension on the Myeloma Beacon a few days ago. Today we have a few more, rather scary, I must say!, details (see: http://tinyurl.com/39j8buw ).

My first impression, as I have already written on  (!) Facebook pages (1. my personal Wall AND 2. my blog’s FB page AND 3. the new multiple myeloma support group’s FB Wall), is that this goes to show that too much of a (possibly) good thing may not be such a…good thing!

And this is precisely why I always stick to the recommended dose of any new supplement that I decide to try. Indeed, I usually start out by taking less than the recommended dose (as I did back in January 2006 with curcumin, after all). For example, right now I am testing Reishi (scientific name: Ganoderma lucidum), which seizes myeloma cells by the neck and squeezes the life out of ‘em…sorry, got a bit carried away there…Anyway, I have been taking one Reishi extract capsule, not two (two capsules=recommended daily serving), just to be on the safe side. So far, so good. Next week I will go up to the (recommended) two-capsule dose…then, blood tests in June.

And, I would like to add, the “too much of a good thing might not be so good” theory is also why I will never ever take more than eight grams of curcumin…

I would also like to note that my friend Sherlock and I tested resveratrol a couple of years ago (see my July 2008 results)…and even though we remained stable, our MM markers went up a wee bit, so I was very disappointed and will almost certainly NOT test this substance again. Oh, another thing: my cholesterol went UP with resveratrol, not down as expected. Weird.

Hmmm, a question just popped into my mind: are any of you having good results from resveratrol? If so, please leave a comment on this post…thank you!

Oh, just a quick P.S. Today is our 11th wedding anniversary. Yes, Stefano and I got married on May 8th, 1999 (=the year I was diagnosed with MGUS, in fact), and we are still happily married. We are about to go into town to have lunch and enjoy this sunny day (finally, some sun! It has been raining almost non-stop in Firenze for the past several days!)…so I have to go get ready….Ciao, everyone, have a great weekend!!!

Buon anniversario, Ste, TVTTTB! :-D

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