Guideliens disagree how long to follow lymphomas but the literaure favors those who do NOT recommend routine imaging. NCCN (DLCL and follicular) recommends:
•Repeating all positive studies at end of treatment •Imaging every 3 to 6 months for 5 years, then yearly or as clinically indicated, based on disease site and clinical presentation
In contrast to the North American guidelines, the 2007 European Society of Medical Oncology (ESMO) specifically advises against routine imaging except to evaluate residual disease. These guidelines recommend:
•PET scan at end of treatment, if available •Minimal radiologic examinations in patients with DLBCL at 6, 12, and 24 months after end of treatment, when indicated by site of disease
2007 International Working Group Guidelines for Lymphoma advise that follow-up will vary according to whether treatment was administered in a clinical trial or clinical practice, or whether it was given with curative or palliative intent. The panel advises against routine imaging given the lack of evidence supporting its role.