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Cold Spring Harbor study shows how “bookmarking” genes before cell division accelerates their subsequent reactivatio

Posted Oct 12 2011 10:23pm
Cold Spring Harbor study shows how “bookmarking” genes before cell division accelerates their subsequent reactivation: NCI Cancer Center News

In order for cells of different types to maintain their identities even after repeated rounds of cell division, each cell must “remember” which genes were active before division and pass along that memory to its daughter cells. Cells deal with this challenge by deploying a “bookmarking” process... This bookmark, the [Cold Spring Harbor Laboratory] scientists show, is a histone molecule that has undergone a chemical modification called acetylation, which alters its interactions with DNA as well as with proteins that bind to it.

Click here to read full press release from Cold Spring Harbor Laboratory .

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