It is official now. I signed the protocol and I entered the Phase One study for R7112. It was pouring when I left MSKCC and the rain soaked my copy of the protocol... but I can still read what this drug might do:
We are testing the safety of different doses of a new oral medicine called R7112. We want to find out what R7112 does to you and your cancer, good or bad. R7112 blocks a molecule called "MDM2" in tumor cell. This causes the cell to make more of a molecule called "p53". Large amounts of p53 then cause a tumor cell to self-destruct.
I will tell you more details tomorrow. Right now I am going to dream with large amounts of p53