inhibiting the growth of cancer tumor blood vessels
Posted May 25 2010 12:00am
As I mentioned recently, one area of research and treatment for cancer is the inhibition of the growth of blood vessels in cancer tumors. When cancer grows in a tumor, the tumor grows its own supporting blood vessels.
Today I found an article about a study at the Karolinska Institutet in Sweden of a DNA vaccine that affects a cancer tumor’s new growth of blood vessels. Investigators identified a protein, DLL4, Delta-like ligand 4, that helps to regulate the growth of new blood vessels. The vaccine suppresses the expression of this protein and leads to an increase of blood vessels that are nonfunctional and, therefore, slows the growth of the tumor’s blood vessels.