Health knowledge made personal
Join this community!
› Share page:
Go
Search posts:

Hormone Replacement Therapy (HRT) and Breast Cancer Risk

Posted Oct 18 2010 9:13pm
 

 

Weekly Health Update:


Hormone Replacement Therapy (HRT) and Breast Cancer Risk


"A critical weekly review of important new research findings for health-conscious readers..."

 

 

By, Robert A. Wascher, MD, FACS

Image of MD, FACS Robert A. Wascher


Updated:  10/7/2010

The information in this column is intended for informational purposes only, and does not constitute medical advice or recommendations by the author.  Please consult with your physician before making any lifestyle or medication changes, or if you have any other concerns regarding your health.


 

Welcome to Weekly Health Update

 


“A critical weekly review of important new research findings for health-conscious readers”


pink-ribbon-image

    

OCTOBER IS NATIONAL BREAST CANCER

 

 

AWARENESS MONTH

 

 


 
HORMONE REPLACEMENT THERAPY (HRT)

AND BREAST CANCER RISK

 

The rising incidence of breast cancer, year-after-year, over the past 50 years in the United States (and in many other industrialized countries) has been attributed to a variety of factors, including environmental contaminants, rising obesity levels, and increased compliance with annual screening mammograms, among others. However, one factor that has been given inadequate attention, in my view, is that of hormone replacement therapy (HRT), despite nearly a century of data showing a strong linkage between lifetime exposure to the female hormones estrogen and progesterone and the risk of developing breast cancer.

 

In 2002, the enormous, randomized, prospective, blinded Women’s Health Initiative (WHI) study published its preliminary results, and prematurely terminated its combination HRT study because of an alarming increase in the incidence of breast cancer in the group of women who had been secretly randomized to receive combination HRT medications for menopausal symptoms.

 

Despite subsequent updates from the WHI, which have shown, essentially, a doubling of breast cancer risk after more than 5 years of HRT use, there was initially a great deal of resistance to the WHI’s findings (and the findings of other similar clinical research trials) linking HRT use with an increased risk of developing breast cancer.

 

Now, a new national Canadian public health study offers additional powerful clinical research data linking HRT use with breast cancer risk, and reveals the equally strong link between declining HRT use and the declining breast cancer incidence in Canada. This study appears in the current issue of the Journal of the National Cancer Institute.

 

In this study, 1,200 women between the ages of 50 and 69 participated in the National Population Health Survey between 1996 and 2006. Just prior to the 2002 release of the WHI study’s results, 13 percent of these women regularly used combination HRT. By December 2004, only 5 percent of the postmenopausal women participating in this study were still taking HRT medications. During this same period, the incidence of breast cancer in this large group of Canadian women decreased by about 10 percent. (Importantly, compliances rates with screening mammograms did not change during the course of this clinical research study.)

 

Thus, between 2002 and 2004, when HRT use significantly declined, the incidence of breast cancer decreased by about 10 percent in Canada. Moreover, this significant decrease in breast cancer incidence occurred without any change in mammogram rates.

 

This study, as with other recent studies, adds to the overwhelming research data linking HRT use with an increased risk of developing breast cancer. As I tell my own patients who are approaching menopause, it is best to avoid HRT altogether. If you are already taking HRT medications, then ask your doctor to help you in weaning yourself off of these medications.

 

For a deeper evidence-based discussion of the links between HRT and breast cancer risk, order your copy of my new book,A Cancer Prevention Guide for the Human Race,” fromAmazon,Barnes & Noble,Books-A-Million,Vroman’s Bookstore, and other fine bookstores!


I and the staff of Weekly Health Update would again like to take this opportunity to thank the more than 100,000 health-conscious people, from around the world, who visit our premier global health information website every month. (As of 9/16/2010, more than 1,000,000 health-conscious people have logged onto Weekly Health Update so far this year!) As always, we enjoy receiving your stimulating feedback and questions, and I will continue to try and personally answer as many of your inquiries as I possibly can.



Disclaimer:  As always, my advice to readers is to seek the advice of your physicianbeforemaking any significant changes in medications, diet, or level of physical activity


Dr. Wascher is an oncologic surgeon, professor of surgery, cancer researcher, oncology consultant, and a widely published author


For a different perspective on Dr. Wascher, please click on the following YouTube link: 

Texas Blues Jam



Send your feedback to Dr. Wascher at: 

rwascher@doctorwascher.net


Dr. Wascher's Biography


Links to Other Health & Wellness Sites


http://doctorwascher.com/


Copyright 2007 - 2010

 

Robert A. Wascher, MD, FACS

 

All rights reserved


Dr. Wascher's Archives:

10-7-2010:   Hormone Replacement Therapy (HRT) and Breast Cancer Risk

10-3-2010:   Mammograms Between 40 and 49 Years of Age

9-26-2010:   Vitamin D, Cardiovascular Disease, Cancer, and Death

9-19-2010:   Fruits and Vegetables Improve Memory

9-12-2010:    Low-Carb Diet and Risk of Death

9-5-2010:     Non-Compliance with Hormonal Therapy for Breast Cancer and Risk of Death

8-29-2010:  New Treatment for Irritable Bowel Syndrome (IBS)

8-22-2010:  Lactoferrin Reduces Abdominal (Visceral) Obesity

8-15-2010:  Blueberries, Obesity, Diabetes and Metabolic Syndrome

8-8-2010:    High LDL Cholesterol in Young Adults and Heart Disease Risk in Middle Age

8-1-2010:      Physician Error

7-25-2010:   Obesity and Cancer Risk

7-18-2010:  Vitamin D Reduces Risk of Cognitive Decline & Dementia

7-11-2010:  All Forms of Hormone Replacement Therapy (HRT) Increase Breast Cancer Risk

7-4-2010:   Irritable Bowel Syndrome: Cause Discovered?

6-27-2010:  Soy, Curcumin & Prostate Cancer Risk

6-20-2010:  Green Tea Epicatechin Reduces Heart Damage & CHF

6-13-2010:  Diacylglycerol (Diglyceride) Oil Reduces Obesity

6-6-2010:   Important New Advance in the Breast Cancer Treatment: Intraoperative Radiation Therapy

5-30-2010:  Medical Research Studies & “Spin”

5-23-2010:  Soy & Curcumin Reduce Prostate-Specific Antigen (PSA)

5-16-2010:  Coffee & the Risk of Death from Heart Disease & Cancer

5-9-2010:     Soy Foods & Stomach Cancer Risk

5-2-2010:    Chemotherapy for Breast Cancer & Memory Loss

4-25-2010:    Smoking, Teenagers & Tobacco Company Advertising

4-18-2010:    Coffee Improves HDL Cholesterol Levels

4-11-2010:   Cruciferous Vegetables, Soy & Breast Cancer Risk

4-4-2010:     Avodart (Dutasteride) & Prostate Cancer Prevention

3-28-2010:   Aspirin & Breast Cancer Survival

3-21-2010:   Obesity, Alcohol & Liver Disease

3-14-2010:   Nuts, Diet & Obesity

3-7-2010:      Walnuts, Cholesterol, LDL & Triglycerides

2-28-2010:   Soy Isoflavones & Recurrent Prostate Cancer

2-21-2010:   Testosterone Supplements in Frail Elderly Men

2-14-2010:   Pancreatic Cancer Risk, Sodas & Juice

2-7-2010:      Vitamin D, Cardiovascular Disease & Death

1-31-2010:   Concord Grape Juice Improves Memory

1-24-2010:   Mozart, Music, Babies & Health

1-17-2010:   Breast Cancer, Physical Therapy & Lymphedema

1-10-2010:   Prevention of Surgical Site Infections (SSIs) after Surgery

1-3-2010:     Ginkgo Biloba, Memory & Cognitive Health

12-20-2009:  CT Scans & Cancer Risk

12-13-2009:  Soy Isoflavones Decrease Breast Cancer Recurrence Risk

12-6-2009:   Salt (Sodium) Intake, Stroke & Cardiovascular Disease

11-29-2009:  Exercise & Prostate Cancer Risk

11-22-2009:  Genistein (Soy Isoflavone) & Prostate Cancer

11-15-2009:  Breast Cancer Treatment & Chronic Pain

1-8-2009:      Vitamin D & Breast Cancer Risk

11-1-2009:   Exercise & Prostate Cancer Risk

10-25-2009:  HPV Virus & Risk of Breast Cancer

10-18-2009:  Post-Cholecystectomy Syndrome (Symptoms after Gallbladder Surgery)

10-11-2009: Vitamin D & Falls in the Elderly

10-4-2009:    Surgery, NSQIP, Complications & Death

9-27-2009     Stress, Heart Disease, Exercise & Death

9-20-2009:    Vitamin D & Colorectal Cancer Survival

9-13-2009:    H1N1 Swine Flu Update

9-7-2009:      Green Tea, Aging & Lifespan

8-30-2009:    Irritable Bowel Syndrome (IBS), Diet & Fiber

8-23-2009:   Update on Prostate Cancer and Cryotherapy

8-16-2009:    Exercise Improves Lymphedema Symptoms in Breast Cancer Survivors

8-9-2009:    Breast Cancer Recurrence, Death & Vitamin D

8-2-2009:    Honesty, Dishonesty & Brain Function

7-26-2009:    Coronary Artery CT Scans & Cancer Risk

7-19-2009:    Hormone Replacement Therapy (HRT) & Ovarian Cancer

7-12-2009:    Breast Cancer & Metformin (Glucophage)

7-5-2009:     Prostate Cancer & Green Tea

6-28-2009:    Air Pollution & the Risk of Deep Venous Thrombosis (DVT)

6-21-2009:    Red Yeast Rice, Statins & Cholesterol

6-14-2009:    Bone Marrow Stem Cell Transplant & Congestive Heart Failure (CHF)

6-7-2009:     Diet, Soy & Breast Cancer Risk

5-31-2009:    Diet and Prostate Cancer Risk

5-24-2009:    Diabetes, Glucose Control & Death

5-17-2009:    Drug Company Marketing & Physician Prescribing Bias

5-10-2009:    Hemorrhoids & Surgery

5-3-2009:      Statin Drugs & Blood Clots (Thromboembolism)

4-26-2009:    Are We Really Losing the War on Cancer?

4-19-2009:     Exercise in Middle Age & Risk of Death

4-12-2009:    Can Chronic Stress Harm Your Heart?

4-5-2009:      Does PSA Testing for Prostate Cancer Save Lives?

3-22-2009:    CABG Surgery vs. PCI in Diabetics with Coronary Artery Disease; Sweetened Beverages and Coronary Artery Disease

3-15-2009:    Depression, Stress, Anger & Heart Disease

3-8-2009:     Coronary Artery Disease: CABG vs. Stents?; Swimming Lessons & Drowning Risk in Children

3-1-2009:     Aspirin & Colorectal Cancer Prevention; Fish Oil & Respiratory Infections in Children

2-22-2009:  Health Differences Between Americans & Europeans; Lycopene & Prostate Cancer

2-15-2009:  Statin Drugs & Death Rates; Physical Activity, Breast Cancer & Sex Hormones

2-8-2009:    Hormone Replacement Therapy (HRT) & Breast Cancer; Stool DNA Testing & Cancer of the Colon & Rectum

2-1-2009:   Obesity and the Complications of Diverticulosis (Diverticulitis & Bleeding); Obesity, Weight Loss & Urinary Incontinence

1-25-2009:  Prostate Cancer, Fatigue & Exercise; Does your Surgeon “Warm-up” Before Surgery?

1-18-2009:  Cancer and Vitamins; Teenagers, MySpace and Risky Behaviors

1-11-2009:  Exercise Reverses Some Effects of Fatty Meals; Vitamin C and Blood Pressure

1-4-2009:    Secondhand Smoke & Heart Attack Risk; Poor Physical Fitness During Childhood & Heart Disease Risk During Adulthood

12-28-2008:  Stress & Your Risk of Heart Attack; Vitamin D & the Prevention of Colon & Rectal Polyps

12-21-2008:  Breast Cancer Incidence & Hormone Replacement Therapy; Circumcision & the Risk of HPV & HIV Infection

12-14-2008:  Vitamin E, Vitamin C and Selenium Do Not Prevent Cancer; Postscript: A Possible Cure for Down’s Syndrome

12-7-2008:    Generic vs. Brand-Name Drugs, Stress & Breast Cancer Survival

11-30-2008:  A Possible Cure for Down’s Syndrome?; Smoking & Cognitive Decline; Calcium & Vitamin D & Breast Cancer Risk

11-23-2008:   Breast Cancer & Fish Oil; Lymphedema after Breast Cancer Treatment; Vasectomy & Prostate Cancer Risk

11-16-2008:   Vitamin E & Vitamin C: No Impact on Cardiovascular Disease Risk; Does Lack of Sleep Increase Stroke & Heart Attack Risk in Hypertensive Patients?

11-9-2008:     Statins Cut Heart Attack Risk Even with Normal Cholesterol Levels; Statins & PSA Level

11-2-2008:     Radiation Treatment of Prostate Cancer & Second Cancers; Sexual Content on TV & Teen Pregnancy Risk

10-26-2008:   Smoking & Quality of Life

10-19-2008:   Agent Orange & Prostate Cancer

10-12-2008:   Pomegranate Juice & Prostate Cancer

10-5-2008:    Central Obesity & Dementia; Diet, Vitamin D, Calcium, & Colon Cancer

9-28-2008:    Publication & Citation Bias in Favor of Industry-Funded Research?

9-21-2008:    Does Tylenol® (Acetaminophen) Cause Asthma?

9-14-208:     Arthroscopic Knee Surgery- No Better than Placebo?; A Healthy Lifestyle Prevents Stroke

8-23-2008:   Alcohol Abuse Before & After Military Deployment; Running & Age; Running & Your Testicles

8-12-2008:   Green Tea & Diabetes; Breastfeeding & Adult Cholesterol Levels; Fish Oil & Senile Macular Degeneration

8-3-2008:    Exercise & Weight Loss; Green Tea, Folic Acid & Breast Cancer Risk; Foreign Language Interpreters & ICU Patients

 

7-26-2008:   Viagra & Sexual Function in Women; Patient-Reported Adverse Hospital Events; Curcumin & Pancreatic Cancer

7-13-2008:   Erectile Dysfunction & Frequency of Sex; Muscle Strength & Mortality in Men; Cryoablation for Prostate Cancer

7-6-2008:   Sleep, Melatonin & Breast Cancer Risk; Mediterranean Diet & Cancer Risk; New Treatment for Varicose Veins

6-29-2008:   Bone Marrow Stem Cells & Liver Failure; Vitamin D & Colorectal Cancer Survival; Green Tea & Colorectal Cancer

6-22-2008:   Obesity, Lifestyle & Heart Disease; Effects of Lifestyle & Nutrition on Prostate Cancer; Ginkgo Biloba, Ulcerative Colitis & Colorectal Cancer

6-15-2008:   Preventable Deaths after Coronary Artery Bypass Graft (CABG) Surgery; Green Tea & Colorectal Cancer; Attention-Deficit/Hyperactivity Disorder (ADHD) & St. John’s Wort

6-8-2008:   Vitamin D & Prostate Cancer Risk; Radiofrequency Ablation (RFA) of Kidney (Renal) Cancer; Antisense Telomerase & Cancer

6-2-2008:   Acute Coronary Syndrome- Do You Know the Symptoms?; Green Tea & Lung Cancer; Episiotomy & Subsequent Deliveries- An Unkind Cut

5-25-2008:   Early Childhood Screening Predicts Later Behavioral Problems; Psychiatric Disorders Among Parents of Autistic Children; Social & Psychiatric Profiles of Young Adults Born Prematurely

5-18-2008:   Can Statins Reverse Coronary Artery Disease?; Does Breast Ultrasound Improve Breast Cancer Detection?; Preventive Care Services at Veterans Administration (VA) Medical Centers

5-11-2008:   Smoking Cessation & Risk of Death; Childhood Traumas & Adult Suicide Risk; “White Coat Hypertension” & Risk of Cardiovascular Disease

5-4-2008:   Super-Size Me: Fast Food’s Effects on Your Liver; Exercise, Weight & Coronary Artery Disease; Contamination of Surgical Instruments in the Operating Room

4-27-2008:   Stents vs. Bypass Surgery for Coronary Artery Disease; The “DASH” Hypertension Diet & Cardiovascular Disease Prevention; Testosterone Therapy for Women with Decreased Sexual Desire & Function

4-20-2008:   BRCA Breast Cancer Mutations & MRI Scans; Bladder Cancer Prevention with Broccoli?; Diabetes: Risk of Death Due to Heart Attack & Stroke

4-13-2008:   Breast Cancer Recurrence & Hormone Replacement Therapy (HRT); Carotid Artery Disease: Surgery vs. Stents?; Statin Drugs & Cancer Prevention

4-6-2008:   Human Papilloma Virus (HPV), Pap Smear Results & Cervical Cancer; Human Papilloma Virus (HPV) Infection & Oral Cancer; Hormone Replacement Therapy (HRT) & the Risk of Gastroesophageal Reflux Disorder (GERD)

3-30-2008:   Abdominal Obesity & the Risk of Death in Women; Folic Acid Pretreatment & Heart Attacks; Pancreatic Cancer Regression after Injections of Bacteria

3-23-2008:   Age of Transfused Blood & Risk of Complications after Surgery; Obesity, Blood Pressure & Heart Size in Children

3-16-2008:   Benefits of a Full Drug Coverage Plan for Medicare Patients?; Parent-Teen Conversations about Sex; Soy (Genistein) & Prostate Cancer

3-9-2008:   Flat Colorectal Adenomas & Cancer; Health Risks after Stopping Hormone Replacement Therapy (HRT); Television, Children & Obesity 

3-2-2008:   Medication & Risk of Death After Heart Attack; Hormone Replacement Therapy (HRT) & Mammogram Results; Selenium: Cancer, Heart Disease & Death

2-23-2008:   Universal Healthcare Insurance Study; Glucosamine & Arthritis

2-17-2008:   Exceptional Longevity in Men; Testosterone & Risk of Prostate Cancer; Smoking & Pre-malignant Colorectal Polyps

2-10-2008:   Thrombus Aspiration from Coronary Arteries; Intensive Management of Diabetes & Death; Possible Cure for  Down's Syndrome?

2-3-2008:   Vitamin D & Cardiovascular Health; Vitamin D & Breast Cancer; Green Tea & Colorectal Cancer

1-27-2008:   Colorectal Cancer, Esophageal Cancer & Pancreatic Cancer: Update from the 2008 American Society of Clinical Oncology's Gastrointestinal Cancers Symposium

1-20-2008:   Testosterone Levels & Risk of Fractures in Elderly Men; Air Pollution & DNA Damage in Sperm; Statins & Trauma Survival in the Elderly

1-12-2008:   Statins, Diabetes & Stroke and Obesity; GERD & Esophageal Cancer

1-7-2008:   Testosterone Supplements in Elderly Men; Colorectal Cancer-- Reasons for Poor Compliance with Screening Recommendations

12-31-2007:   Minority Women, Hormone Replacement Therapy & Breast Cancer; Does Health Insurance Improve Health?

12-23-2007:  Is Coffee Safe After a Heart Attack?; Impact of Divorce on the Environment; Hypertension & the Risk of Dementia; Emotional Vitality & the Risk of Heart Disease

12-16-2007:   Honey vs. Dextromethorphan vs. No Treatment for Kids with Night-Time Cough, Acupuncture & Hot Flashes in Women with Breast Cancer, Physical Activity & the Risk of Death, Mediterranean Diet & Mortality  

12-11-2007:   Bias in Medical Research; Carbon Nanotubes & Radiofrequency: A New Weapon Against Cancer?; Childhood Obesity & Risk of Adult Heart Disease

12-2-2007:   Obesity & Risk of Cancer; Testosterone Level & Risk of Death; Drug Company Funding of Research & Results; Smoking & the Risk of Colon & Rectal Cancer 


Dr. Wascher's Home Page


Post a comment
Write a comment:

Related Searches