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Breast Cancer Metastasis Gene Identified

Posted Oct 11 2009 12:00am
New research from the Wistar Institute has identified two genes involved with breast cancer metastasis.  Metastasis is a complex, poorly understood process by which cancer spreads from one area of the body to other areas.

Investigators were able to to identify a gene involved in breast cancer metastasis by placing breast cancer tumor cells that do not usually spread in the fat pads of mouse mammary glands and then reducing the function of genes that block metastasis.  This gene is called KLF17.  Once this gene was identified, the investigators did additional studies to confirm the importance of this gene in breast cancer metastasis.  In doing so, they discovered a second gene, called Id1, involved with breast cancer metastasis.  In a nutshell, breast cancer metastasis took place in breast cancer cells that were low in KLF17 and high in Id1.  You can read the full Wistar Institute press release HERE.

These finding are an important step in breast cancer research and breast cancer treatment.  By finding genes that are involved with the spread of breast cancer to other tissues in the body, medical professionals might be able to develop better breast cancer detection methods and improve breast cancer treatment.

While science continues to make new discoveries in breast cancer treatment, breast cancer prevention is one area where we can take individual steps.  To learn more about some of the things you can do to reduce breast cancer risk, read my book Fight Now: Eat & Live Proactively Against Breast Cancer at
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